Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| natural killer cell | 7 studies | 19% ± 2% | |
| precursor B cell | 6 studies | 33% ± 8% | |
| epithelial cell | 5 studies | 31% ± 12% | |
| plasmacytoid dendritic cell | 5 studies | 19% ± 5% | |
| B cell | 4 studies | 22% ± 6% | |
| CD8-positive, alpha-beta T cell | 4 studies | 18% ± 1% | |
| CD4-positive, alpha-beta T cell | 3 studies | 19% ± 1% | |
| conventional dendritic cell | 3 studies | 30% ± 12% | |
| non-classical monocyte | 3 studies | 22% ± 6% | |
| pro-B cell | 3 studies | 25% ± 4% | |
| naive B cell | 3 studies | 20% ± 4% |
Insufficient scRNA-seq data for expression of DDX54 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3006.33 | 1445 / 1445 | 100% | 48.29 | 183 / 183 |
| pancreas | 100% | 2973.08 | 328 / 328 | 100% | 39.46 | 178 / 178 |
| uterus | 100% | 3543.04 | 170 / 170 | 100% | 48.72 | 458 / 459 |
| ovary | 100% | 3303.58 | 180 / 180 | 100% | 42.51 | 429 / 430 |
| thymus | 100% | 3559.19 | 653 / 653 | 100% | 48.87 | 603 / 605 |
| intestine | 100% | 2907.88 | 966 / 966 | 100% | 55.78 | 525 / 527 |
| skin | 100% | 4001.44 | 1809 / 1809 | 100% | 55.75 | 470 / 472 |
| breast | 100% | 3352.34 | 459 / 459 | 99% | 41.66 | 1111 / 1118 |
| stomach | 100% | 2824.42 | 359 / 359 | 99% | 52.06 | 284 / 286 |
| prostate | 100% | 3041.03 | 245 / 245 | 99% | 49.63 | 497 / 502 |
| kidney | 100% | 2619.55 | 89 / 89 | 99% | 36.30 | 890 / 901 |
| liver | 100% | 1897.85 | 225 / 226 | 99% | 32.15 | 402 / 406 |
| lung | 100% | 2996.17 | 578 / 578 | 98% | 44.85 | 1137 / 1155 |
| bladder | 100% | 3297.57 | 21 / 21 | 98% | 51.31 | 496 / 504 |
| brain | 98% | 1809.77 | 2602 / 2642 | 99% | 36.14 | 700 / 705 |
| adrenal gland | 100% | 3486.19 | 258 / 258 | 95% | 32.13 | 218 / 230 |
| adipose | 100% | 3112.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3197.94 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 77.14 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 64.86 | 29 / 29 |
| muscle | 100% | 4928.77 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3490.33 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 49.20 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 44.90 | 1 / 1 |
| heart | 97% | 1790.91 | 835 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 92% | 2413.53 | 857 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030520 | Biological process | estrogen receptor signaling pathway |
| GO_0016070 | Biological process | RNA metabolic process |
| GO_0006364 | Biological process | rRNA processing |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0006396 | Biological process | RNA processing |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0003724 | Molecular function | RNA helicase activity |
| GO_0030331 | Molecular function | nuclear estrogen receptor binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | DDX54 |
| Protein name | ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (ATP-dependent RNA helicase DP97) (DEAD box RNA helicase 97 kDa) (DEAD box protein 54) DEAD-box helicase 54 RNA helicase (EC 3.6.4.13) |
| Synonyms | |
| Description | FUNCTION: Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors. . |
| Accessions | ENST00000306014.10 [Q8TDD1-1] ENST00000552375.1 Q8TDD1 ENST00000314045.11 [Q8TDD1-2] H0YHH7 ENST00000546898.1 F8VRX4 ENST00000551344.1 H0YHZ9 |