I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hematopoietic stem cell | 3 studies | 23% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| hematopoietic stem cell | 3 studies | 23% ± 8% |
Insufficient scRNA-seq data for expression of AVP at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 87% | 27.63 | 77 / 89 | 6% | 0.14 | 52 / 901 |
| adrenal gland | 77% | 7.31 | 199 / 258 | 3% | 0.07 | 7 / 230 |
| brain | 69% | 7479.56 | 1830 / 2642 | 2% | 0.08 | 12 / 705 |
| adipose | 60% | 10.22 | 721 / 1204 | 0% | 0 | 0 / 0 |
| breast | 54% | 6.86 | 249 / 459 | 0% | 0.00 | 1 / 1118 |
| liver | 39% | 3.42 | 88 / 226 | 5% | 0.16 | 22 / 406 |
| peripheral blood | 40% | 4.50 | 373 / 929 | 0% | 0 | 0 / 0 |
| bladder | 33% | 2.05 | 7 / 21 | 5% | 0.26 | 26 / 504 |
| heart | 26% | 2.54 | 220 / 861 | 0% | 0 | 0 / 0 |
| thymus | 23% | 2.81 | 150 / 653 | 1% | 0.02 | 7 / 605 |
| prostate | 23% | 3.04 | 56 / 245 | 0% | 0 | 0 / 502 |
| lung | 21% | 2.22 | 120 / 578 | 2% | 0.04 | 22 / 1155 |
| ovary | 18% | 1.98 | 33 / 180 | 3% | 0.05 | 11 / 430 |
| muscle | 19% | 2.08 | 156 / 803 | 0% | 0 | 0 / 0 |
| uterus | 15% | 1.53 | 25 / 170 | 4% | 0.08 | 18 / 459 |
| skin | 17% | 18.65 | 304 / 1809 | 1% | 0.02 | 3 / 472 |
| intestine | 16% | 5.09 | 155 / 966 | 1% | 0.03 | 6 / 527 |
| spleen | 15% | 0.92 | 37 / 241 | 0% | 0 | 0 / 0 |
| esophagus | 14% | 1.39 | 199 / 1445 | 1% | 0.03 | 2 / 183 |
| blood vessel | 14% | 1.48 | 182 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 11% | 0.96 | 38 / 359 | 2% | 0.06 | 6 / 286 |
| pancreas | 10% | 1.46 | 32 / 328 | 1% | 0.01 | 1 / 178 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0043154 | Biological process | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| GO_0033574 | Biological process | response to testosterone |
| GO_0007625 | Biological process | grooming behavior |
| GO_0006091 | Biological process | generation of precursor metabolites and energy |
| GO_0014049 | Biological process | positive regulation of glutamate secretion |
| GO_0032849 | Biological process | positive regulation of cellular pH reduction |
| GO_0030307 | Biological process | positive regulation of cell growth |
| GO_0007165 | Biological process | signal transduction |
| GO_0033138 | Biological process | positive regulation of peptidyl-serine phosphorylation |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0090201 | Biological process | negative regulation of release of cytochrome c from mitochondria |
| GO_0045907 | Biological process | positive regulation of vasoconstriction |
| GO_0031394 | Biological process | positive regulation of prostaglandin biosynthetic process |
| GO_0050891 | Biological process | multicellular organismal-level water homeostasis |
| GO_0045471 | Biological process | response to ethanol |
| GO_0051970 | Biological process | negative regulation of transmission of nerve impulse |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0002125 | Biological process | maternal aggressive behavior |
| GO_0006833 | Biological process | water transport |
| GO_0046718 | Biological process | symbiont entry into host cell |
| GO_0042711 | Biological process | maternal behavior |
| GO_0070371 | Biological process | ERK1 and ERK2 cascade |
| GO_0003084 | Biological process | positive regulation of systemic arterial blood pressure |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0007621 | Biological process | negative regulation of female receptivity |
| GO_0035094 | Biological process | response to nicotine |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0070528 | Biological process | protein kinase C signaling |
| GO_0042310 | Biological process | vasoconstriction |
| GO_0035176 | Biological process | social behavior |
| GO_0007626 | Biological process | locomotory behavior |
| GO_0098992 | Cellular component | neuronal dense core vesicle |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0030669 | Cellular component | clathrin-coated endocytic vesicle membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0005829 | Cellular component | cytosol |
| GO_0030141 | Cellular component | secretory granule |
| GO_0043027 | Molecular function | cysteine-type endopeptidase inhibitor activity involved in apoptotic process |
| GO_0031895 | Molecular function | V1B vasopressin receptor binding |
| GO_0005185 | Molecular function | neurohypophyseal hormone activity |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0004672 | Molecular function | protein kinase activity |
| GO_0031894 | Molecular function | V1A vasopressin receptor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005184 | Molecular function | neuropeptide hormone activity |
| Gene name | AVP |
| Protein name | Arginine vasopressin (Neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal) (Arginine vasopressin isoform B) Arginine vasopressin-neurophysin II Vasopressin-neurophysin 2-copeptin (AVP-NPII) [Cleaved into: Arg-vasopressin (Arginine-vasopressin); Neurophysin 2 (Neurophysin-II); Copeptin] Arginine vasopressin isoform A Arginine vasopressin |
| Synonyms | ARVP hCG_39618 VP |
| Description | FUNCTION: [Neurophysin 2]: Specifically binds vasopressin.; FUNCTION: [Arg-vasopressin]: Has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2) . . |
| Accessions | P01185 Q9UMM9 X5D8U4 ENST00000380293.3 X5DQP6 S6BQ34 Q9HB76 |
