Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell of lymphatic vessel | 25 studies | 41% ± 16% | |
endothelial cell | 24 studies | 33% ± 16% | |
pericyte | 24 studies | 29% ± 15% | |
smooth muscle cell | 14 studies | 28% ± 10% | |
endothelial cell of vascular tree | 12 studies | 33% ± 14% | |
GABAergic neuron | 5 studies | 23% ± 4% | |
muscle cell | 4 studies | 19% ± 2% | |
glutamatergic neuron | 4 studies | 30% ± 8% | |
interneuron | 4 studies | 33% ± 23% | |
capillary endothelial cell | 3 studies | 39% ± 25% | |
adipocyte | 3 studies | 18% ± 0% | |
oligodendrocyte precursor cell | 3 studies | 23% ± 4% | |
astrocyte | 3 studies | 17% ± 3% | |
neuron | 3 studies | 20% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 22% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 1756.09 | 457 / 459 | 94% | 7.51 | 1054 / 1118 |
thymus | 100% | 1584.79 | 652 / 653 | 91% | 8.76 | 549 / 605 |
bladder | 95% | 874.38 | 20 / 21 | 87% | 6.14 | 436 / 504 |
lung | 90% | 791.18 | 523 / 578 | 86% | 6.68 | 991 / 1155 |
esophagus | 71% | 413.46 | 1032 / 1445 | 96% | 9.10 | 175 / 183 |
uterus | 94% | 576.24 | 159 / 170 | 68% | 5.29 | 313 / 459 |
intestine | 74% | 478.73 | 718 / 966 | 84% | 5.05 | 442 / 527 |
ovary | 64% | 400.82 | 116 / 180 | 86% | 5.12 | 370 / 430 |
prostate | 89% | 643.53 | 219 / 245 | 56% | 2.99 | 283 / 502 |
brain | 66% | 524.98 | 1750 / 2642 | 75% | 11.89 | 529 / 705 |
stomach | 46% | 221.92 | 164 / 359 | 87% | 7.06 | 250 / 286 |
skin | 57% | 310.03 | 1038 / 1809 | 71% | 11.38 | 334 / 472 |
kidney | 40% | 254.82 | 36 / 89 | 76% | 38.38 | 681 / 901 |
adipose | 100% | 2601.16 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 1944.97 | 1320 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 6% | 21.70 | 19 / 328 | 88% | 6.30 | 157 / 178 |
adrenal gland | 7% | 21.21 | 19 / 258 | 84% | 10.90 | 194 / 230 |
tonsil | 0% | 0 | 0 / 0 | 78% | 5.45 | 35 / 45 |
heart | 75% | 723.84 | 643 / 861 | 0% | 0 | 0 / 0 |
muscle | 67% | 369.39 | 542 / 803 | 0% | 0 | 0 / 0 |
liver | 11% | 43.92 | 25 / 226 | 54% | 2.75 | 221 / 406 |
lymph node | 0% | 0 | 0 / 0 | 38% | 1.95 | 11 / 29 |
eye | 0% | 0 | 0 / 0 | 11% | 0.37 | 9 / 80 |
spleen | 8% | 41.50 | 20 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001525 | Biological process | angiogenesis |
GO_0010812 | Biological process | negative regulation of cell-substrate adhesion |
GO_0009749 | Biological process | response to glucose |
GO_0045766 | Biological process | positive regulation of angiogenesis |
GO_0007165 | Biological process | signal transduction |
GO_0014070 | Biological process | response to organic cyclic compound |
GO_0031100 | Biological process | animal organ regeneration |
GO_0014823 | Biological process | response to activity |
GO_0071363 | Biological process | cellular response to growth factor stimulus |
GO_0043537 | Biological process | negative regulation of blood vessel endothelial cell migration |
GO_0050928 | Biological process | negative regulation of positive chemotaxis |
GO_0016525 | Biological process | negative regulation of angiogenesis |
GO_0007281 | Biological process | germ cell development |
GO_0048014 | Biological process | Tie signaling pathway |
GO_0001666 | Biological process | response to hypoxia |
GO_0072012 | Biological process | glomerulus vasculature development |
GO_0010467 | Biological process | gene expression |
GO_0009612 | Biological process | response to mechanical stimulus |
GO_0060135 | Biological process | maternal process involved in female pregnancy |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0042995 | Cellular component | cell projection |
GO_0005102 | Molecular function | signaling receptor binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0030971 | Molecular function | receptor tyrosine kinase binding |
Gene name | ANGPT2 |
Protein name | Angiopoietin-2 (ANG-2) Angiopoietin-2 |
Synonyms | |
Description | FUNCTION: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling . Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1 . In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal . Involved in the regulation of lymphangiogenesis . . |
Accessions | ENST00000629816.3 [O15123-3] ENST00000523120.2 O15123 E7EVQ3 ENST00000338312.10 [O15123-2] ENST00000325203.9 [O15123-1] |