NRIP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071392Biological processcellular response to estradiol stimulus
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0032922Biological processcircadian regulation of gene expression
GO_0007623Biological processcircadian rhythm
GO_0019915Biological processlipid storage
GO_0001543Biological processovarian follicle rupture
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005730Cellular componentnucleolus
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0001650Cellular componentfibrillar center
GO_0000118Cellular componenthistone deacetylase complex
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0016922Molecular functionnuclear receptor binding
GO_0035259Molecular functionnuclear glucocorticoid receptor binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0005102Molecular functionsignaling receptor binding
GO_0030331Molecular functionnuclear estrogen receptor binding
GO_0046965Molecular functionnuclear retinoid X receptor binding
GO_0003713Molecular functiontranscription coactivator activity
GO_0005515Molecular functionprotein binding
GO_0042826Molecular functionhistone deacetylase binding

IV. Literature review

[source]
Gene nameNRIP1
Protein nameNuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140)
Nuclear receptor interacting protein 1
Synonyms
DescriptionFUNCTION: Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. Involved in the regulation of ovarian function (By similarity). Plays a role in renal development . .

AccessionsENST00000400202.5
ENST00000638122.1
P48552
ENST00000318948.7
C9J130
ENST00000411932.1
ENST00000400199.5
A0A1B0GUG9