TNFSF15 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TNFSF15 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TNFSF15 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006955Biological processimmune response
GO_0007250Biological processactivation of NF-kappaB-inducing kinase activity
GO_0006919Biological processactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO_0005615Cellular componentextracellular space
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005164Molecular functiontumor necrosis factor receptor binding
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding
GO_0005125Molecular functioncytokine activity

IV. Literature review

[source]
Gene nameTNFSF15
Protein nameTumor necrosis factor (Ligand) superfamily, member 15
Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor) [Cleaved into: Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form]
TNF superfamily member 15
SynonymsTL1
VEGI
DescriptionFUNCTION: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. .

AccessionsD9N2U0
ENST00000374045.5 [O95150-1]
X6R8I9
ENST00000374044.1
O95150