Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 3 studies | 23% ± 6% | |
| fibroblast | 3 studies | 31% ± 7% |
Insufficient scRNA-seq data for expression of CCL13 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 95% | 515.62 | 547 / 578 | 84% | 36.68 | 972 / 1155 |
| skin | 63% | 205.61 | 1145 / 1809 | 61% | 11.18 | 287 / 472 |
| bladder | 57% | 202.33 | 12 / 21 | 66% | 18.30 | 333 / 504 |
| intestine | 64% | 610.66 | 615 / 966 | 53% | 8.69 | 277 / 527 |
| thymus | 42% | 50.72 | 277 / 653 | 67% | 14.74 | 407 / 605 |
| breast | 67% | 122.08 | 308 / 459 | 42% | 6.08 | 470 / 1118 |
| esophagus | 53% | 99.83 | 770 / 1445 | 44% | 8.06 | 81 / 183 |
| adipose | 87% | 313.12 | 1049 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 75% | 143.16 | 193 / 258 | 9% | 1.50 | 21 / 230 |
| stomach | 31% | 44.82 | 111 / 359 | 50% | 6.24 | 143 / 286 |
| pancreas | 5% | 3.78 | 15 / 328 | 75% | 16.56 | 133 / 178 |
| tonsil | 0% | 0 | 0 / 0 | 78% | 12.60 | 35 / 45 |
| uterus | 16% | 27.38 | 28 / 170 | 54% | 9.66 | 246 / 459 |
| lymph node | 0% | 0 | 0 / 0 | 62% | 8.27 | 18 / 29 |
| blood vessel | 52% | 123.63 | 693 / 1335 | 0% | 0 | 0 / 0 |
| kidney | 22% | 28.67 | 20 / 89 | 16% | 1.55 | 145 / 901 |
| prostate | 33% | 42.41 | 80 / 245 | 4% | 0.21 | 22 / 502 |
| ovary | 4% | 4.43 | 8 / 180 | 24% | 3.28 | 103 / 430 |
| heart | 28% | 37.27 | 243 / 861 | 0% | 0 | 0 / 0 |
| liver | 1% | 0.74 | 2 / 226 | 14% | 1.42 | 57 / 406 |
| muscle | 5% | 4.71 | 37 / 803 | 0% | 0 | 0 / 0 |
| brain | 0% | 0 | 0 / 2642 | 4% | 0.98 | 30 / 705 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.24 | 3 / 80 |
| peripheral blood | 1% | 2.05 | 10 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006954 | Biological process | inflammatory response |
| GO_0043547 | Biological process | positive regulation of GTPase activity |
| GO_0007165 | Biological process | signal transduction |
| GO_0006935 | Biological process | chemotaxis |
| GO_0006874 | Biological process | intracellular calcium ion homeostasis |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0031640 | Biological process | killing of cells of another organism |
| GO_0070098 | Biological process | chemokine-mediated signaling pathway |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0048245 | Biological process | eosinophil chemotaxis |
| GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0008009 | Molecular function | chemokine activity |
| GO_0048020 | Molecular function | CCR chemokine receptor binding |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CCL13 |
| Protein name | C-C motif chemokine 13 (CK-beta-10) (Monocyte chemoattractant protein 4) (Monocyte chemotactic protein 4) (MCP-4) (NCC-1) (Small-inducible cytokine A13) [Cleaved into: C-C motif chemokine 13, long chain; C-C motif chemokine 13, medium chain; C-C motif chemokine 13, short chain] CC-chemokine (Chemokine (C-C motif) ligand 13, isoform CRA_a) C-C motif chemokine ligand 13 |
| Synonyms | NCC1 SCYA13 MCP4 hCG_29297 |
| Description | FUNCTION: Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. |
| Accessions | J3QLQ9 ENST00000577681.1 Q99616 ENST00000225844.7 O95690 |