I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| connective tissue cell | 3 studies | 35% ± 14% | |
| fibroblast | 3 studies | 34% ± 11% | |
| mesothelial cell | 3 studies | 22% ± 6% | |
| astrocyte | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| connective tissue cell | 3 studies | 35% ± 14% | |
| fibroblast | 3 studies | 34% ± 11% | |
| mesothelial cell | 3 studies | 22% ± 6% | |
| astrocyte | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of GSTM2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 3948.52 | 651 / 653 | 93% | 4.60 | 560 / 605 |
| brain | 92% | 1214.74 | 2429 / 2642 | 100% | 9.94 | 702 / 705 |
| adrenal gland | 99% | 2513.96 | 255 / 258 | 88% | 3.35 | 203 / 230 |
| ovary | 100% | 9018.91 | 180 / 180 | 87% | 3.36 | 372 / 430 |
| kidney | 98% | 1900.42 | 87 / 89 | 79% | 3.06 | 710 / 901 |
| pancreas | 94% | 1141.38 | 307 / 328 | 79% | 2.86 | 141 / 178 |
| prostate | 100% | 5579.34 | 245 / 245 | 71% | 2.17 | 356 / 502 |
| skin | 93% | 2447.09 | 1687 / 1809 | 77% | 2.81 | 363 / 472 |
| breast | 100% | 3505.09 | 458 / 459 | 70% | 3.11 | 780 / 1118 |
| lung | 95% | 1748.76 | 551 / 578 | 70% | 3.75 | 805 / 1155 |
| uterus | 100% | 4410.45 | 170 / 170 | 57% | 2.32 | 261 / 459 |
| bladder | 100% | 4080.48 | 21 / 21 | 51% | 7.32 | 255 / 504 |
| esophagus | 98% | 2797.49 | 1417 / 1445 | 49% | 3.43 | 89 / 183 |
| stomach | 100% | 2579.79 | 359 / 359 | 30% | 0.53 | 87 / 286 |
| intestine | 100% | 3213.00 | 962 / 966 | 23% | 0.40 | 122 / 527 |
| ureter | 0% | 0 | 0 / 0 | 100% | 32.07 | 1 / 1 |
| blood vessel | 99% | 2572.90 | 1322 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 99% | 1958.37 | 238 / 241 | 0% | 0 | 0 / 0 |
| adipose | 99% | 2347.77 | 1189 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 98% | 1770.96 | 784 / 803 | 0% | 0 | 0 / 0 |
| heart | 88% | 1089.59 | 757 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 88% | 3.82 | 70 / 80 |
| liver | 58% | 649.57 | 131 / 226 | 25% | 0.61 | 102 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 48% | 0.94 | 14 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 38% | 0.87 | 17 / 45 |
| peripheral blood | 30% | 275.05 | 282 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0060315 | Biological process | negative regulation of ryanodine-sensitive calcium-release channel activity |
| GO_0070458 | Biological process | cellular detoxification of nitrogen compound |
| GO_0043651 | Biological process | linoleic acid metabolic process |
| GO_0098869 | Biological process | cellular oxidant detoxification |
| GO_0055119 | Biological process | relaxation of cardiac muscle |
| GO_0060316 | Biological process | positive regulation of ryanodine-sensitive calcium-release channel activity |
| GO_0018916 | Biological process | nitrobenzene metabolic process |
| GO_0010881 | Biological process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
| GO_0042178 | Biological process | xenobiotic catabolic process |
| GO_0010880 | Biological process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| GO_0014809 | Biological process | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion |
| GO_0051122 | Biological process | hepoxilin biosynthetic process |
| GO_0006749 | Biological process | glutathione metabolic process |
| GO_0071313 | Biological process | cellular response to caffeine |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0045171 | Cellular component | intercellular bridge |
| GO_0005829 | Cellular component | cytosol |
| GO_0016529 | Cellular component | sarcoplasmic reticulum |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0004602 | Molecular function | glutathione peroxidase activity |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0043295 | Molecular function | glutathione binding |
| GO_0005504 | Molecular function | fatty acid binding |
| GO_0004364 | Molecular function | glutathione transferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GSTM2 |
| Protein name | glutathione transferase (EC 2.5.1.18) Glutathione S-transferase (EC 2.5.1.18) Glutathione S-transferase Mu 2 (EC 2.5.1.18) (GST class-mu 2) (GSTM2-2) Glutathione S-transferase mu 2 |
| Synonyms | GST4 |
| Description | FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Participates in the formation of novel hepoxilin regioisomers . . |
| Accessions | E9PHN7 F6XZQ7 ENST00000460717.7 [P28161-2] E9PLF1 ENST00000369831.6 E9PGV1 P28161 ENST00000414179.6 ENST00000241337.9 [P28161-1] ENST00000442650.5 [P28161-2] E9PHN6 Q0D2I8 ENST00000369829.2 ENST00000369827.7 ENST00000467579.7 A8HT81 |
