GFRA1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031175Biological processneuron projection development
GO_0035860Biological processglial cell-derived neurotrophic factor receptor signaling pathway
GO_0001822Biological processkidney development
GO_0050731Biological processpositive regulation of peptidyl-tyrosine phosphorylation
GO_0008584Biological processmale gonad development
GO_0038179Biological processneurotrophin signaling pathway
GO_0016477Biological processcell migration
GO_0007399Biological processnervous system development
GO_0007166Biological processcell surface receptor signaling pathway
GO_0009897Cellular componentexternal side of plasma membrane
GO_0043235Cellular componentreceptor complex
GO_0005886Cellular componentplasma membrane
GO_0070062Cellular componentextracellular exosome
GO_0005794Cellular componentGolgi apparatus
GO_0043025Cellular componentneuronal cell body
GO_0019898Cellular componentextrinsic component of membrane
GO_0098797Cellular componentplasma membrane protein complex
GO_0005771Cellular componentmultivesicular body
GO_0030424Cellular componentaxon
GO_0038023Molecular functionsignaling receptor activity
GO_0005030Molecular functionneurotrophin receptor activity
GO_0005102Molecular functionsignaling receptor binding
GO_0005178Molecular functionintegrin binding
GO_0016167Molecular functionglial cell-derived neurotrophic factor receptor activity

IV. Literature review

[source]
Gene nameGFRA1
Protein nameAlternative protein GFRA1
GDNF family receptor alpha-1 (GDNF receptor alpha-1) (GDNFR-alpha-1) (GFR-alpha-1) (RET ligand 1) (TGF-beta-related neurotrophic factor receptor 1)
GDNF family receptor alpha 1
GDNF family receptor alpha-1 (GDNF receptor alpha-1)
SynonymsRETL1
GDNFRA
TRNR1
DescriptionFUNCTION: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity). .

FUNCTION: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. .

AccessionsENST00000682489.1
A0A804HJK2
ENST00000369236.5 [P56159-2]
ENST00000490345.2
P56159
ENST00000683792.1
ENST00000369234.5 [P56159-1]
ENST00000682194.1
ENST00000682743.1 [P56159-2]
ENST00000355422.11 [P56159-1]
ENST00000684105.1 [P56159-2]
ENST00000439649.8 [P56159-2]
ENST00000683474.1
A0A804HL20
L8ECC2