ARTN report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ARTN at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ARTN at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0061146Biological processPeyer's patch morphogenesis
GO_0097021Biological processlymphocyte migration into lymphoid organs
GO_0050930Biological processinduction of positive chemotaxis
GO_0007422Biological processperipheral nervous system development
GO_0007411Biological processaxon guidance
GO_0007405Biological processneuroblast proliferation
GO_0035860Biological processglial cell-derived neurotrophic factor receptor signaling pathway
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0030116Molecular functionglial cell-derived neurotrophic factor receptor binding
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding
GO_0030971Molecular functionreceptor tyrosine kinase binding
GO_0008083Molecular functiongrowth factor activity

IV. Literature review

[source]
Gene nameARTN
Protein nameArtemin (Enovin) (Neublastin)
Artemin
SynonymsEVN
DescriptionFUNCTION: Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. .

AccessionsENST00000498139.6 [Q5T4W7-3]
ENST00000372354.3 [Q5T4W7-1]
ENST00000372359.10 [Q5T4W7-1]
ENST00000414809.7 [Q5T4W7-3]
ENST00000479128.5
ENST00000438616.3 [Q5T4W7-2]
ENST00000474592.1
E9PIK2
E9PN22
ENST00000472435.1
ENST00000491846.5
E9PLG3
ENST00000477048.5
Q5T4W7
ENST00000471394.6