Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 43 studies | 47% ± 21% | |
| capillary endothelial cell | 17 studies | 64% ± 13% | |
| endothelial cell of artery | 16 studies | 65% ± 23% | |
| endothelial cell of lymphatic vessel | 15 studies | 43% ± 14% | |
| fibroblast | 14 studies | 28% ± 11% | |
| pericyte | 14 studies | 38% ± 22% | |
| vein endothelial cell | 12 studies | 41% ± 15% | |
| endothelial cell of vascular tree | 11 studies | 40% ± 17% | |
| ciliated cell | 7 studies | 29% ± 10% | |
| connective tissue cell | 6 studies | 31% ± 11% | |
| club cell | 5 studies | 28% ± 7% | |
| respiratory goblet cell | 5 studies | 37% ± 15% | |
| type I pneumocyte | 4 studies | 27% ± 8% | |
| secretory cell | 4 studies | 40% ± 21% | |
| glomerular endothelial cell | 4 studies | 87% ± 6% | |
| epithelial cell | 4 studies | 43% ± 20% | |
| goblet cell | 4 studies | 26% ± 7% | |
| basal cell | 4 studies | 45% ± 23% | |
| duct epithelial cell | 3 studies | 27% ± 14% | |
| podocyte | 3 studies | 44% ± 6% | |
| smooth muscle cell | 3 studies | 21% ± 4% | |
| mucus secreting cell | 3 studies | 43% ± 5% | |
| myofibroblast cell | 3 studies | 36% ± 14% | |
| hepatocyte | 3 studies | 30% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 6 studies | 31% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 13756.17 | 226 / 226 | 100% | 149.64 | 404 / 406 |
| prostate | 100% | 8747.80 | 245 / 245 | 99% | 199.31 | 498 / 502 |
| thymus | 100% | 12130.79 | 650 / 653 | 100% | 111.07 | 602 / 605 |
| ovary | 97% | 3527.57 | 175 / 180 | 100% | 118.18 | 430 / 430 |
| brain | 99% | 4937.14 | 2621 / 2642 | 98% | 47.62 | 688 / 705 |
| stomach | 100% | 5296.06 | 359 / 359 | 97% | 58.49 | 276 / 286 |
| breast | 100% | 11011.82 | 459 / 459 | 96% | 106.71 | 1077 / 1118 |
| intestine | 99% | 4718.72 | 958 / 966 | 97% | 58.49 | 512 / 527 |
| lung | 100% | 18911.32 | 578 / 578 | 92% | 69.86 | 1058 / 1155 |
| adrenal gland | 100% | 4737.04 | 258 / 258 | 87% | 69.33 | 200 / 230 |
| bladder | 100% | 4887.76 | 21 / 21 | 87% | 47.62 | 438 / 504 |
| kidney | 100% | 10909.74 | 89 / 89 | 86% | 73.81 | 779 / 901 |
| uterus | 100% | 6077.76 | 170 / 170 | 85% | 60.16 | 392 / 459 |
| esophagus | 95% | 4271.66 | 1376 / 1445 | 89% | 37.85 | 163 / 183 |
| pancreas | 58% | 1251.15 | 189 / 328 | 98% | 97.91 | 174 / 178 |
| skin | 72% | 1972.60 | 1303 / 1809 | 76% | 34.00 | 359 / 472 |
| spleen | 100% | 9682.34 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 68.57 | 1 / 1 |
| heart | 100% | 12674.51 | 858 / 861 | 0% | 0 | 0 / 0 |
| adipose | 99% | 11741.76 | 1197 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 5695.79 | 1327 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 93% | 3215.04 | 744 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 90% | 37.63 | 72 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 80% | 33.32 | 36 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 45% | 12.21 | 13 / 29 |
| peripheral blood | 1% | 41.37 | 12 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0072659 | Biological process | protein localization to plasma membrane |
| GO_0065003 | Biological process | protein-containing complex assembly |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0012505 | Cellular component | endomembrane system |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0005634 | Cellular component | nucleus |
| GO_0031800 | Molecular function | type 3 metabotropic glutamate receptor binding |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0043495 | Molecular function | protein-membrane adaptor activity |
| GO_0019902 | Molecular function | phosphatase binding |
| GO_0008013 | Molecular function | beta-catenin binding |
| GO_0031799 | Molecular function | type 2 metabotropic glutamate receptor binding |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | NHERF2 |
| Protein name | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1) NHERF family PDZ scaffold protein 2 SLC9A3R2 protein |
| Synonyms | SLC9A3R2 |
| Description | FUNCTION: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3 . May also act as scaffold protein in the nucleus. . |
| Accessions | ENST00000424542.7 [Q15599-1] ENST00000565855.5 ENST00000432365.6 [Q15599-2] H3BQS0 ENST00000563587.5 Q15599 H3BMF5 ENST00000567504.5 ENST00000561844.5 Q6NTG0 H3BN50 ENST00000566198.1 [Q15599-3] H3BUQ9 |