PIK3IP1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
T cell	27 studies	30% ± 14%	Explore
CD4-positive, alpha-beta T cell	27 studies	45% ± 15%	Explore
CD8-positive, alpha-beta T cell	27 studies	34% ± 13%	Explore
regulatory T cell	25 studies	44% ± 15%	Explore
natural killer cell	23 studies	31% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	19 studies	48% ± 19%	Explore
B cell	17 studies	27% ± 10%	Explore
naive B cell	16 studies	26% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	46% ± 19%	Explore
gamma-delta T cell	15 studies	31% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	29% ± 9%	Explore
mature NK T cell	13 studies	30% ± 9%	Explore
mucosal invariant T cell	13 studies	33% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	27% ± 11%	Explore
memory B cell	11 studies	21% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	38% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	35% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	37% ± 16%	Explore
T follicular helper cell	8 studies	42% ± 17%	Explore
macrophage	7 studies	24% ± 4%	Explore
innate lymphoid cell	6 studies	31% ± 10%	Explore
mast cell	5 studies	20% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	44% ± 22%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	37% ± 10%	Explore
lymphocyte	4 studies	27% ± 10%	Explore
CD4-positive helper T cell	4 studies	35% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	22% ± 3%	Explore
squamous epithelial cell	3 studies	39% ± 20%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	25% ± 6%	Explore
leukocyte	3 studies	23% ± 2%	Explore
exhausted T cell	3 studies	30% ± 12%	Explore
endothelial cell	3 studies	17% ± 2%	Explore
epithelial cell	3 studies	24% ± 8%	Explore
capillary endothelial cell	3 studies	20% ± 5%	Explore
ciliated cell	3 studies	17% ± 2%	Explore
Mueller cell	3 studies	24% ± 1%	Explore
basal cell	3 studies	25% ± 7%	Explore
astrocyte	3 studies	23% ± 3%	Explore
type I pneumocyte	3 studies	25% ± 6%	Explore
group 3 innate lymphoid cell	3 studies	41% ± 2%	Explore
T-helper 17 cell	3 studies	36% ± 12%	Explore
oligodendrocyte	3 studies	21% ± 1%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	45% ± 12%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	31% ± 13%	Explore
double negative thymocyte	3 studies	41% ± 6%	Explore
microglial cell	3 studies	22% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	31% ± 8%	Explore
lung	7 studies	22% ± 3%	Explore
brain	5 studies	20% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	99%	5007.13	649 / 653	100%	111.66	604 / 605
brain	99%	3108.34	2611 / 2642	100%	68.44	704 / 705
prostate	99%	3577.60	242 / 245	99%	44.97	499 / 502
breast	100%	5307.09	459 / 459	97%	42.29	1090 / 1118
lung	100%	6053.81	576 / 578	96%	48.80	1114 / 1155
kidney	99%	3155.90	88 / 89	97%	50.37	876 / 901
intestine	99%	4984.34	955 / 966	95%	33.52	499 / 527
bladder	95%	4208.95	20 / 21	97%	50.38	487 / 504
adrenal gland	95%	5031.39	245 / 258	94%	59.55	217 / 230
uterus	99%	4300.96	168 / 170	90%	35.40	412 / 459
stomach	95%	2336.56	341 / 359	93%	30.00	265 / 286
esophagus	98%	2890.28	1417 / 1445	86%	21.88	157 / 183
ovary	94%	2674.98	169 / 180	90%	28.03	385 / 430
skin	84%	4968.97	1524 / 1809	70%	19.98	330 / 472
pancreas	39%	529.80	128 / 328	99%	68.65	176 / 178
lymph node	0%	0	0 / 0	100%	67.23	29 / 29
spleen	100%	9468.39	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	21.03	1 / 1
adipose	99%	5327.15	1196 / 1204	0%	0	0 / 0
blood vessel	97%	3710.58	1299 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	48.80	42 / 45
peripheral blood	90%	4972.57	835 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	84%	20.24	67 / 80
heart	83%	1704.27	712 / 861	0%	0	0 / 0
liver	12%	148.04	26 / 226	63%	17.59	254 / 406
muscle	67%	1295.77	538 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0051898	Biological process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0005615	Cellular component	extracellular space
GO_0005886	Cellular component	plasma membrane
GO_0141039	Molecular function	phosphatidylinositol 3-kinase inhibitor activity
GO_0004175	Molecular function	endopeptidase activity
GO_0005102	Molecular function	signaling receptor binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PIK3IP1
Protein name	Phosphoinositide-3-kinase-interacting protein 1 (PI3K-interacting protein 1) (Kringle domain-containing protein HGFL) Phosphoinositide-3-kinase-interacting protein 1 (Kringle domain-containing protein HGFL)
Synonyms	HGFL
Description	FUNCTION: Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity. . FUNCTION: Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity. .
Accessions	ENST00000402249.7 [Q96FE7-2] ENST00000215912.10 [Q96FE7-1] ENST00000443175.1 C9JMK5 Q96FE7 ENST00000441972.5 [Q96FE7-4]

PIK3IP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review