Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 38 studies | 53% ± 20% | |
monocyte | 28 studies | 49% ± 23% | |
classical monocyte | 28 studies | 60% ± 17% | |
conventional dendritic cell | 28 studies | 45% ± 17% | |
non-classical monocyte | 25 studies | 58% ± 16% | |
dendritic cell | 18 studies | 42% ± 19% | |
fibroblast | 18 studies | 29% ± 16% | |
mast cell | 16 studies | 33% ± 10% | |
myeloid cell | 16 studies | 48% ± 23% | |
neutrophil | 13 studies | 65% ± 18% | |
plasmacytoid dendritic cell | 11 studies | 24% ± 8% | |
basal cell | 10 studies | 32% ± 12% | |
alveolar macrophage | 8 studies | 49% ± 12% | |
endothelial cell | 7 studies | 21% ± 4% | |
secretory cell | 7 studies | 39% ± 16% | |
mononuclear phagocyte | 6 studies | 54% ± 22% | |
leukocyte | 6 studies | 34% ± 16% | |
epithelial cell | 6 studies | 54% ± 22% | |
intermediate monocyte | 6 studies | 52% ± 23% | |
endothelial cell of vascular tree | 5 studies | 30% ± 5% | |
pericyte | 5 studies | 21% ± 6% | |
monocyte-derived dendritic cell | 4 studies | 59% ± 22% | |
microglial cell | 4 studies | 29% ± 17% | |
inflammatory macrophage | 4 studies | 37% ± 21% | |
smooth muscle cell | 4 studies | 23% ± 6% | |
connective tissue cell | 4 studies | 42% ± 21% | |
goblet cell | 3 studies | 27% ± 12% | |
tissue-resident macrophage | 3 studies | 49% ± 18% | |
granulocyte | 3 studies | 45% ± 7% | |
luminal cell of prostate epithelium | 3 studies | 42% ± 5% | |
hematopoietic precursor cell | 3 studies | 33% ± 13% | |
progenitor cell of mammary luminal epithelium | 3 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 4537.75 | 578 / 578 | 98% | 58.93 | 1132 / 1155 |
uterus | 99% | 1082.41 | 168 / 170 | 95% | 56.94 | 437 / 459 |
breast | 93% | 951.01 | 429 / 459 | 92% | 31.85 | 1028 / 1118 |
ovary | 94% | 923.70 | 169 / 180 | 88% | 26.77 | 377 / 430 |
intestine | 82% | 896.14 | 789 / 966 | 99% | 58.52 | 522 / 527 |
stomach | 76% | 1257.78 | 274 / 359 | 99% | 54.74 | 284 / 286 |
bladder | 86% | 1174.81 | 18 / 21 | 86% | 43.58 | 433 / 504 |
esophagus | 61% | 528.87 | 879 / 1445 | 96% | 48.08 | 176 / 183 |
skin | 72% | 1400.18 | 1298 / 1809 | 82% | 44.82 | 389 / 472 |
thymus | 76% | 613.34 | 497 / 653 | 59% | 18.58 | 358 / 605 |
kidney | 57% | 635.47 | 51 / 89 | 59% | 13.65 | 536 / 901 |
pancreas | 18% | 124.71 | 58 / 328 | 94% | 88.23 | 167 / 178 |
prostate | 81% | 751.55 | 199 / 245 | 22% | 3.47 | 109 / 502 |
spleen | 100% | 1365.24 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 35.36 | 45 / 45 |
adipose | 98% | 2077.93 | 1181 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 93% | 1341.97 | 1245 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 92% | 12284.66 | 856 / 929 | 0% | 0 | 0 / 0 |
adrenal gland | 68% | 452.78 | 175 / 258 | 13% | 6.07 | 31 / 230 |
lymph node | 0% | 0 | 0 / 0 | 76% | 32.32 | 22 / 29 |
heart | 62% | 742.70 | 538 / 861 | 0% | 0 | 0 / 0 |
brain | 25% | 193.40 | 650 / 2642 | 34% | 9.78 | 239 / 705 |
liver | 20% | 169.66 | 45 / 226 | 17% | 5.20 | 71 / 406 |
muscle | 5% | 24.25 | 39 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0090200 | Biological process | positive regulation of release of cytochrome c from mitochondria |
GO_2001268 | Biological process | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
GO_0051917 | Biological process | regulation of fibrinolysis |
GO_0007165 | Biological process | signal transduction |
GO_0006935 | Biological process | chemotaxis |
GO_0001934 | Biological process | positive regulation of protein phosphorylation |
GO_0007596 | Biological process | blood coagulation |
GO_0045742 | Biological process | positive regulation of epidermal growth factor receptor signaling pathway |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0010755 | Biological process | regulation of plasminogen activation |
GO_0043388 | Biological process | positive regulation of DNA binding |
GO_0034112 | Biological process | positive regulation of homotypic cell-cell adhesion |
GO_2001243 | Biological process | negative regulation of intrinsic apoptotic signaling pathway |
GO_0038195 | Biological process | urokinase plasminogen activator signaling pathway |
GO_0030162 | Biological process | regulation of proteolysis |
GO_0030155 | Biological process | regulation of cell adhesion |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005576 | Cellular component | extracellular region |
GO_0035579 | Cellular component | specific granule membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0019898 | Cellular component | extrinsic component of membrane |
GO_0005925 | Cellular component | focal adhesion |
GO_0009986 | Cellular component | cell surface |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0098637 | Cellular component | protein complex involved in cell-matrix adhesion |
GO_0042995 | Cellular component | cell projection |
GO_1905370 | Cellular component | serine-type endopeptidase complex |
GO_0030377 | Molecular function | urokinase plasminogen activator receptor activity |
GO_0019899 | Molecular function | enzyme binding |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0005102 | Molecular function | signaling receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | PLAUR |
Protein name | Urokinase plasminogen activator surface receptor Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87) Plasminogen activator, urokinase receptor Urokinase plasminogen activator receptor |
Synonyms | MO3 UPAR |
Description | FUNCTION: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. FUNCTION: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. . FUNCTION: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. . FUNCTION: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. . FUNCTION: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. . FUNCTION: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. . FUNCTION: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. . FUNCTION: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. . FUNCTION: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. . |
Accessions | M0R1I2 ENST00000340093.8 [Q03405-1] ENST00000599546.1 M0R383 ENST00000593714.5 Q6GY32 M0R0Y4 ENST00000221264.8 [Q03405-3] M0QX27 ENST00000597107.1 ENST00000339082.7 [Q03405-2] Q9UPI5 M0R2E9 ENST00000593939.5 ENST00000595038.5 ENST00000601723.5 Q03405 M0R0L1 M0QYS6 M0R0H5 ENST00000602141.5 ENST00000593447.5 ENST00000599892.5 M0QYR6 |