FCN2 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell of sinusoid	4 studies	39% ± 13%	Explore
endothelial cell	3 studies	42% ± 24%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of FCN2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	93%	151.01	228 / 245	79%	3.78	399 / 502
adrenal gland	100%	1116.25	258 / 258	46%	23.87	105 / 230
liver	100%	2005.78	226 / 226	43%	5.36	176 / 406
breast	95%	154.63	438 / 459	48%	3.54	532 / 1118
kidney	85%	252.28	76 / 89	33%	1.46	301 / 901
spleen	100%	202.24	240 / 241	0%	0	0 / 0
thymus	85%	113.27	556 / 653	10%	7.64	61 / 605
adipose	91%	139.60	1098 / 1204	0%	0	0 / 0
ovary	71%	24.16	128 / 180	10%	0.26	41 / 430
bladder	52%	18.38	11 / 21	1%	0.06	4 / 504
uterus	31%	9.39	53 / 170	6%	0.26	29 / 459
pancreas	28%	13.03	93 / 328	3%	0.10	5 / 178
peripheral blood	22%	11.25	208 / 929	0%	0	0 / 0
skin	16%	5.80	292 / 1809	1%	0.06	5 / 472
blood vessel	16%	9.38	216 / 1335	0%	0	0 / 0
esophagus	16%	5.03	225 / 1445	1%	0.01	1 / 183
heart	16%	5.75	134 / 861	0%	0	0 / 0
stomach	14%	6.06	51 / 359	1%	0.01	2 / 286
lung	12%	3.67	67 / 578	3%	0.07	34 / 1155
brain	6%	1.52	162 / 2642	3%	0.06	20 / 705
tonsil	0%	0	0 / 0	9%	0.15	4 / 45
intestine	4%	1.59	37 / 966	1%	0.07	5 / 527
muscle	1%	0.31	12 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0002752	Biological process	cell surface pattern recognition receptor signaling pathway
GO_1903028	Biological process	positive regulation of opsonization
GO_0050829	Biological process	defense response to Gram-negative bacterium
GO_0050830	Biological process	defense response to Gram-positive bacterium
GO_0006508	Biological process	proteolysis
GO_0008228	Biological process	opsonization
GO_0043654	Biological process	recognition of apoptotic cell
GO_0001867	Biological process	complement activation, lectin pathway
GO_0005615	Cellular component	extracellular space
GO_0009897	Cellular component	external side of plasma membrane
GO_0005576	Cellular component	extracellular region
GO_0070062	Cellular component	extracellular exosome
GO_0005581	Cellular component	collagen trimer
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0072562	Cellular component	blood microparticle
GO_1905370	Cellular component	serine-type endopeptidase complex
GO_2001065	Molecular function	mannan binding
GO_0005102	Molecular function	signaling receptor binding
GO_0097367	Molecular function	carbohydrate derivative binding
GO_0048306	Molecular function	calcium-dependent protein binding
GO_0046872	Molecular function	metal ion binding
GO_0003823	Molecular function	antigen binding
GO_0043394	Molecular function	proteoglycan binding
GO_0005515	Molecular function	protein binding

Gene name	FCN2
Protein name	FCN2 protein Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35)
Synonyms	FCNL
Description	FUNCTION: May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. .
Accessions	Q15485 Q14CE6 ENST00000291744.11 [Q15485-1] ENST00000350339.3 [Q15485-2]

FCN2 report