Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 14 studies | 20% ± 4% | |
CD16-positive, CD56-dim natural killer cell, human | 13 studies | 21% ± 6% | |
CD8-positive, alpha-beta T cell | 13 studies | 21% ± 4% | |
effector memory CD8-positive, alpha-beta T cell | 9 studies | 21% ± 5% | |
mature NK T cell | 9 studies | 19% ± 2% | |
gamma-delta T cell | 8 studies | 19% ± 4% | |
CD8-positive, alpha-beta memory T cell | 7 studies | 20% ± 4% | |
T cell | 5 studies | 23% ± 8% | |
CD16-negative, CD56-bright natural killer cell, human | 5 studies | 21% ± 6% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 5 studies | 20% ± 4% | |
effector memory CD8-positive, alpha-beta T cell, terminally differentiated | 5 studies | 20% ± 4% | |
regulatory T cell | 4 studies | 19% ± 1% | |
lymphocyte | 4 studies | 26% ± 8% | |
mucosal invariant T cell | 3 studies | 19% ± 2% | |
plasma cell | 3 studies | 23% ± 6% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 22% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 3060.27 | 180 / 180 | 99% | 28.13 | 427 / 430 |
intestine | 100% | 3104.27 | 964 / 966 | 99% | 25.98 | 523 / 527 |
lung | 100% | 4962.39 | 578 / 578 | 99% | 29.74 | 1141 / 1155 |
kidney | 100% | 2139.40 | 89 / 89 | 98% | 38.39 | 880 / 901 |
breast | 99% | 2573.41 | 454 / 459 | 99% | 26.36 | 1104 / 1118 |
stomach | 99% | 1721.00 | 355 / 359 | 99% | 24.79 | 282 / 286 |
uterus | 100% | 3615.69 | 170 / 170 | 97% | 24.77 | 444 / 459 |
skin | 99% | 1899.57 | 1796 / 1809 | 97% | 37.79 | 458 / 472 |
thymus | 99% | 2202.98 | 646 / 653 | 97% | 18.27 | 587 / 605 |
bladder | 100% | 2112.86 | 21 / 21 | 96% | 22.76 | 482 / 504 |
prostate | 100% | 3224.34 | 245 / 245 | 96% | 17.71 | 480 / 502 |
pancreas | 97% | 1315.99 | 319 / 328 | 98% | 24.54 | 175 / 178 |
adrenal gland | 100% | 3253.80 | 258 / 258 | 95% | 17.54 | 219 / 230 |
esophagus | 97% | 1446.80 | 1398 / 1445 | 97% | 24.32 | 178 / 183 |
brain | 93% | 1127.09 | 2468 / 2642 | 99% | 23.57 | 698 / 705 |
liver | 98% | 1443.97 | 222 / 226 | 89% | 17.22 | 362 / 406 |
spleen | 100% | 12662.01 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 99% | 2535.30 | 1194 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 5199.86 | 917 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 34.97 | 28 / 29 |
tonsil | 0% | 0 | 0 / 0 | 93% | 24.74 | 42 / 45 |
blood vessel | 87% | 1264.78 | 1162 / 1335 | 0% | 0 | 0 / 0 |
heart | 85% | 1008.92 | 728 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 81% | 24.03 | 65 / 80 |
muscle | 33% | 240.47 | 268 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0002250 | Biological process | adaptive immune response |
GO_0032729 | Biological process | positive regulation of type II interferon production |
GO_0001819 | Biological process | positive regulation of cytokine production |
GO_0050852 | Biological process | T cell receptor signaling pathway |
GO_0001817 | Biological process | regulation of cytokine production |
GO_0050798 | Biological process | activated T cell proliferation |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005102 | Molecular function | signaling receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | BTN3A1 |
Protein name | Butyrophilin subfamily 3 member A1 Butyrophilin subfamily 3 member A1 (CD antigen CD277) |
Synonyms | BTF5 |
Description | FUNCTION: Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. . |
Accessions | ENST00000414912.2 [O00481-4] ENST00000425234.6 [O00481-3] ENST00000506698.1 ENST00000427334.5 ENST00000289361.11 [O00481-1] A6PVC0 ENST00000450085.6 E7EPR2 ENST00000476549.6 [O00481-2] O00481 E9PFB8 |