BTN3A1 report

II. Expression across tissues

III. Associated gene sets

GO_0002250Biological processadaptive immune response
GO_0032729Biological processpositive regulation of type II interferon production
GO_0001819Biological processpositive regulation of cytokine production
GO_0050852Biological processT cell receptor signaling pathway
GO_0001817Biological processregulation of cytokine production
GO_0050798Biological processactivated T cell proliferation
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBTN3A1
Protein nameButyrophilin subfamily 3 member A1
Butyrophilin subfamily 3 member A1 (CD antigen CD277)
SynonymsBTF5
DescriptionFUNCTION: Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. .

AccessionsENST00000414912.2 [O00481-4]
ENST00000425234.6 [O00481-3]
ENST00000506698.1
ENST00000427334.5
ENST00000289361.11 [O00481-1]
A6PVC0
ENST00000450085.6
E7EPR2
ENST00000476549.6 [O00481-2]
O00481
E9PFB8