PLXNC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008360Biological processregulation of cell shape
GO_1905806Biological processregulation of synapse pruning
GO_0007162Biological processnegative regulation of cell adhesion
GO_0071526Biological processsemaphorin-plexin signaling pathway
GO_0007155Biological processcell adhesion
GO_0043087Biological processregulation of GTPase activity
GO_0030334Biological processregulation of cell migration
GO_0050772Biological processpositive regulation of axonogenesis
GO_0002116Cellular componentsemaphorin receptor complex
GO_0005886Cellular componentplasma membrane
GO_0150053Cellular componentcerebellar climbing fiber to Purkinje cell synapse
GO_0016020Cellular componentmembrane
GO_0017154Molecular functionsemaphorin receptor activity
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePLXNC1
Protein namePlexin C1 (cDNA FLJ60256, highly similar to Plexin-C1)
Plexin-C1 (Virus-encoded semaphorin protein receptor) (CD antigen CD232)
Plexin C1
SynonymsVESPR
DescriptionFUNCTION: Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity). .

AccessionsF8VUW4
F5H3A2
B4DHQ7
ENST00000258526.9
ENST00000550080.5
F8W1K6
ENST00000549217.5
ENST00000545312.1
F8W095
ENST00000547057.5
ENST00000551850.1
O60486