SELPLG report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046718Biological processsymbiont entry into host cell
GO_0050902Biological processleukocyte adhesive activation
GO_0007155Biological processcell adhesion
GO_0050900Biological processleukocyte migration
GO_0071354Biological processcellular response to interleukin-6
GO_0050901Biological processleukocyte tethering or rolling
GO_0044853Cellular componentplasma membrane raft
GO_0001931Cellular componenturopod
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding
GO_0001618Molecular functionvirus receptor activity

IV. Literature review

[source]
Gene nameSELPLG
Protein nameP-selectin glycoprotein ligand 1 (PSGL-1) (Selectin P ligand) (CD antigen CD162)
Selectin P ligand
Synonyms
DescriptionFUNCTION: A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture. .; FUNCTION: (Microbial infection) Acts as a receptor for enterovirus 71. .

AccessionsENST00000228463.6 [Q14242-2]
ENST00000550948.2 [Q14242-1]
ENST00000388962.4
A0A0C4DFY0
Q14242