MICB report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MICB at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MICB at tissue level.

III. Associated gene sets

GO_0009408Biological processresponse to heat
GO_0002476Biological processantigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO_0002486Biological processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO_0002429Biological processimmune response-activating cell surface receptor signaling pathway
GO_0046629Biological processgamma-delta T cell activation
GO_0001916Biological processpositive regulation of T cell mediated cytotoxicity
GO_0006955Biological processimmune response
GO_0002250Biological processadaptive immune response
GO_0031640Biological processkilling of cells of another organism
GO_0032526Biological processresponse to retinoic acid
GO_0006979Biological processresponse to oxidative stress
GO_0050689Biological processnegative regulation of defense response to virus by host
GO_0005615Cellular componentextracellular space
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0009986Cellular componentcell surface
GO_0005102Molecular functionsignaling receptor binding
GO_0046703Molecular functionnatural killer cell lectin-like receptor binding
GO_0042605Molecular functionpeptide antigen binding

IV. Literature review

[source]
Gene nameMICB
Protein nameMHC Class I chain-related protein (MHC class I polypeptide-related sequence B)
MHC class I polypeptide-related sequence B
MICB antigen (MICB protein)
MHC Class I chain-related protein (MHC class I antigen-related protein B) (MICB)
MHC Class I chain-related protein (MICB)
MHC class I chain-related molecule B
MHC class I chain-related protein B
MHC class I antigen-related protein B
MHC class I polypeptide-related sequence B (MIC-B)
MHC Class I chain-related protein
SynonymsPERB11.2
DescriptionFUNCTION: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. .

AccessionsA0A7D9D6U4
ENST00000252229.7 [Q29980-1]
A0A7D9H8E3
A0A7D9D4N0
A0A7D9D453
ENST00000456351.5
A0A7D9H8B3
A0A1V0E449
ENST00000451789.6
ENST00000538442.5
A0A7D9D6V3
E0AG58
A0A7D9D5J0
ENST00000400313.7
A0A7D9D4H5
A0A7D9D4Q4
ENST00000436655.2
A0A7D9D4T8
ENST00000442104.6 [Q29980-2]
G1EFQ4
A0A7L7TX85
A0A7D9H612
A0A7D9H810
ENST00000442104
A0A385JB84
A0A7D9H880
D2KNA0
ENST00000437651.6
A0A7D9H6S8
A0A7D9H984
A0A7D9H5X0
A0A7D9H6Y9
A0A7D9H960
A0A7D9D449
ENST00000428416.2
ENST00000438954.6
A0A140T979
A0A7D9D5I2
A0A385JB48
A0A7D9D4W1
A0A140T9M6
A0A0G2JH58
A0A7L7TR06
A0A0G2JHB5
A0A7D9D5H6
A0A7D9H996
A0A7L9VVE7
A0A7D9H6V1
A0A7D9H7X8
A0A7D9H821
ENST00000428059.5
A0A3G4S7Y5
Q29980
A0A7D9D493
A0A7D9H8J2
A0A7D9H5X6
ENST00000443156.2
H9B8I7
A0A7D9D6Y8
A0A7D9H654
A0A7D9D431
A0A7D9D4T4
A0A1V0E420
ENST00000619506.1
ENST00000451603.6 [Q29980-1]
A0A140T9D8
ENST00000458032.2
Q0EFB4
A0A7D9H5W2
A0A7D9D6T5
A0A0F7KLE7
A0A7D9H6X5
A0A7D9D441
A0A385JB52
ENST00000436531.6
ENST00000383514.4
ENST00000399150.7 [Q29980-2]
F5H7Q8
A0A0S2VI72
A0A0G2JH91
A0A140T9H4