I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 8 studies | 22% ± 7% | |
| astrocyte | 4 studies | 28% ± 2% | |
| glutamatergic neuron | 3 studies | 38% ± 10% | |
| oligodendrocyte precursor cell | 3 studies | 30% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 8 studies | 22% ± 7% | |
| astrocyte | 4 studies | 28% ± 2% | |
| glutamatergic neuron | 3 studies | 38% ± 10% | |
| oligodendrocyte precursor cell | 3 studies | 30% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 30% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 3848.23 | 2642 / 2642 | 99% | 60.72 | 699 / 705 |
| pancreas | 96% | 1001.64 | 314 / 328 | 76% | 13.24 | 136 / 178 |
| kidney | 87% | 959.00 | 77 / 89 | 52% | 9.68 | 471 / 901 |
| breast | 54% | 527.93 | 246 / 459 | 73% | 16.92 | 814 / 1118 |
| thymus | 34% | 185.39 | 223 / 653 | 83% | 29.07 | 502 / 605 |
| spleen | 85% | 739.94 | 205 / 241 | 0% | 0 | 0 / 0 |
| heart | 79% | 802.82 | 679 / 861 | 0% | 0 | 0 / 0 |
| ovary | 1% | 2.29 | 1 / 180 | 65% | 6.95 | 279 / 430 |
| skin | 40% | 312.90 | 721 / 1809 | 25% | 3.46 | 118 / 472 |
| adrenal gland | 0% | 1.54 | 1 / 258 | 42% | 7.42 | 96 / 230 |
| adipose | 41% | 298.00 | 494 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 5% | 21.07 | 8 / 170 | 36% | 4.33 | 164 / 459 |
| lung | 8% | 38.99 | 48 / 578 | 27% | 3.96 | 317 / 1155 |
| bladder | 14% | 112.81 | 3 / 21 | 8% | 0.80 | 42 / 504 |
| liver | 1% | 3.06 | 2 / 226 | 18% | 3.65 | 73 / 406 |
| intestine | 4% | 21.66 | 43 / 966 | 10% | 0.96 | 52 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 11% | 0.66 | 5 / 45 |
| stomach | 3% | 14.60 | 12 / 359 | 7% | 0.60 | 21 / 286 |
| esophagus | 4% | 20.66 | 65 / 1445 | 4% | 0.33 | 8 / 183 |
| prostate | 7% | 37.38 | 18 / 245 | 0% | 0 | 0 / 502 |
| muscle | 6% | 37.82 | 49 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 5% | 29.48 | 61 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.43 | 3 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0046888 | Biological process | negative regulation of hormone secretion |
| GO_0070328 | Biological process | triglyceride homeostasis |
| GO_0097190 | Biological process | apoptotic signaling pathway |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0002087 | Biological process | regulation of respiratory gaseous exchange by nervous system process |
| GO_0014050 | Biological process | negative regulation of glutamate secretion |
| GO_0006954 | Biological process | inflammatory response |
| GO_0055089 | Biological process | fatty acid homeostasis |
| GO_0002686 | Biological process | negative regulation of leukocyte migration |
| GO_0086004 | Biological process | regulation of cardiac muscle cell contraction |
| GO_0060079 | Biological process | excitatory postsynaptic potential |
| GO_0032244 | Biological process | positive regulation of nucleoside transport |
| GO_0070256 | Biological process | negative regulation of mucus secretion |
| GO_0007165 | Biological process | signal transduction |
| GO_0001973 | Biological process | G protein-coupled adenosine receptor signaling pathway |
| GO_0032900 | Biological process | negative regulation of neurotrophin production |
| GO_0014074 | Biological process | response to purine-containing compound |
| GO_0051930 | Biological process | regulation of sensory perception of pain |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0006612 | Biological process | protein targeting to membrane |
| GO_0002674 | Biological process | negative regulation of acute inflammatory response |
| GO_0060292 | Biological process | long-term synaptic depression |
| GO_0032229 | Biological process | negative regulation of synaptic transmission, GABAergic |
| GO_0050996 | Biological process | positive regulation of lipid catabolic process |
| GO_0003093 | Biological process | regulation of glomerular filtration |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0016042 | Biological process | lipid catabolic process |
| GO_0003085 | Biological process | negative regulation of systemic arterial blood pressure |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0042323 | Biological process | negative regulation of circadian sleep/wake cycle, non-REM sleep |
| GO_0003084 | Biological process | positive regulation of systemic arterial blood pressure |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0007193 | Biological process | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| GO_0050900 | Biological process | leukocyte migration |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0050965 | Biological process | detection of temperature stimulus involved in sensory perception of pain |
| GO_0099509 | Biological process | regulation of presynaptic cytosolic calcium ion concentration |
| GO_0006909 | Biological process | phagocytosis |
| GO_0043268 | Biological process | positive regulation of potassium ion transport |
| GO_1900453 | Biological process | negative regulation of long-term synaptic depression |
| GO_0050995 | Biological process | negative regulation of lipid catabolic process |
| GO_0001659 | Biological process | temperature homeostasis |
| GO_0050890 | Biological process | cognition |
| GO_1900272 | Biological process | negative regulation of long-term synaptic potentiation |
| GO_0007399 | Biological process | nervous system development |
| GO_0070254 | Biological process | mucus secretion |
| GO_0042311 | Biological process | vasodilation |
| GO_0035307 | Biological process | positive regulation of protein dephosphorylation |
| GO_0002793 | Biological process | positive regulation of peptide secretion |
| GO_0051967 | Biological process | negative regulation of synaptic transmission, glutamatergic |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043197 | Cellular component | dendritic spine |
| GO_0043195 | Cellular component | terminal bouton |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0042734 | Cellular component | presynaptic membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0030673 | Cellular component | axolemma |
| GO_0032279 | Cellular component | asymmetric synapse |
| GO_0044305 | Cellular component | calyx of Held |
| GO_0045202 | Cellular component | synapse |
| GO_0048786 | Cellular component | presynaptic active zone |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_0031683 | Molecular function | G-protein beta/gamma-subunit complex binding |
| GO_0032795 | Molecular function | heterotrimeric G-protein binding |
| GO_0031072 | Molecular function | heat shock protein binding |
| GO_0001664 | Molecular function | G protein-coupled receptor binding |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0001609 | Molecular function | G protein-coupled adenosine receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0001883 | Molecular function | purine nucleoside binding |
| Gene name | ADORA1 |
| Protein name | Adenosine receptor A1 |
| Synonyms | |
| Description | FUNCTION: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. FUNCTION: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. . |
| Accessions | ENST00000337894.9 [P30542-1] P30542 ENST00000309502.7 [P30542-1] ENST00000367236.8 [P30542-1] ENST00000367235.1 [P30542-2] S5RC53 |
