Insufficient scRNA-seq data for expression of FGF4 at single-cell level.
Insufficient scRNA-seq data for expression of FGF4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 0% | 0.16 | 5 / 1445 | 6% | 2.95 | 11 / 183 |
stomach | 1% | 0.76 | 5 / 359 | 2% | 0.15 | 5 / 286 |
uterus | 0% | 0 | 0 / 170 | 3% | 7.05 | 14 / 459 |
ovary | 0% | 0 | 0 / 180 | 3% | 0.16 | 12 / 430 |
liver | 0% | 0 | 0 / 226 | 3% | 0.68 | 11 / 406 |
intestine | 2% | 0.89 | 22 / 966 | 0% | 0.02 | 2 / 527 |
breast | 1% | 0.51 | 6 / 459 | 1% | 1.65 | 14 / 1118 |
bladder | 0% | 0 | 0 / 21 | 2% | 1.51 | 11 / 504 |
adipose | 2% | 1.06 | 25 / 1204 | 0% | 0 | 0 / 0 |
lung | 0% | 0 | 0 / 578 | 2% | 0.84 | 18 / 1155 |
prostate | 0% | 0 | 0 / 245 | 1% | 0.07 | 5 / 502 |
pancreas | 0% | 0 | 0 / 328 | 1% | 0.01 | 1 / 178 |
blood vessel | 0% | 0.21 | 6 / 1335 | 0% | 0 | 0 / 0 |
brain | 0% | 0.44 | 8 / 2642 | 0% | 0 | 0 / 705 |
muscle | 0% | 0.23 | 2 / 803 | 0% | 0 | 0 / 0 |
skin | 0% | 0 | 0 / 1809 | 0% | 0.02 | 1 / 472 |
thymus | 0% | 0 | 0 / 653 | 0% | 0.01 | 1 / 605 |
kidney | 0% | 0 | 0 / 89 | 0% | 0.00 | 1 / 901 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042475 | Biological process | odontogenesis of dentin-containing tooth |
GO_0051781 | Biological process | positive regulation of cell division |
GO_0009887 | Biological process | animal organ morphogenesis |
GO_0007165 | Biological process | signal transduction |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_1990830 | Biological process | cellular response to leukemia inhibitory factor |
GO_2000648 | Biological process | positive regulation of stem cell proliferation |
GO_0001934 | Biological process | positive regulation of protein phosphorylation |
GO_0043410 | Biological process | positive regulation of MAPK cascade |
GO_0035116 | Biological process | embryonic hindlimb morphogenesis |
GO_0007267 | Biological process | cell-cell signaling |
GO_0060561 | Biological process | apoptotic process involved in morphogenesis |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0030154 | Biological process | cell differentiation |
GO_0030334 | Biological process | regulation of cell migration |
GO_0060363 | Biological process | cranial suture morphogenesis |
GO_0010463 | Biological process | mesenchymal cell proliferation |
GO_1904019 | Biological process | epithelial cell apoptotic process |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_2000544 | Biological process | regulation of endothelial cell chemotaxis to fibroblast growth factor |
GO_0001502 | Biological process | cartilage condensation |
GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
GO_0060591 | Biological process | chondroblast differentiation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0008543 | Biological process | fibroblast growth factor receptor signaling pathway |
GO_0035019 | Biological process | somatic stem cell population maintenance |
GO_0072089 | Biological process | stem cell proliferation |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005737 | Cellular component | cytoplasm |
GO_0008201 | Molecular function | heparin binding |
GO_0008083 | Molecular function | growth factor activity |
GO_0005104 | Molecular function | fibroblast growth factor receptor binding |
Gene name | FGF4 |
Protein name | Fibroblast growth factor 4 (FGF-4) (Heparin secretory-transforming protein 1) (HST) (HST-1) (HSTF-1) (Heparin-binding growth factor 4) (HBGF-4) (Transforming protein KS3) Fibroblast growth factor (FGF) |
Synonyms | FGF7A HST HSTF1 hCG_27984 KS3 |
Description | FUNCTION: Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. May play a role in embryonic molar tooth bud development via inducing the expression of MSX1, MSX2 and MSX1-mediated expression of SDC1 in dental mesenchyme cells (By similarity). . |
Accessions | ENST00000168712.3 [P08620-1] A0A7U3JW12 P08620 |