Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 8 studies | 23% ± 8% | |
| epithelial cell | 7 studies | 29% ± 12% | |
| endothelial cell | 5 studies | 25% ± 7% | |
| glutamatergic neuron | 5 studies | 34% ± 22% | |
| neuron | 4 studies | 18% ± 3% | |
| astrocyte | 3 studies | 21% ± 4% | |
| basal cell | 3 studies | 27% ± 4% | |
| hepatocyte | 3 studies | 33% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 5394.90 | 226 / 226 | 100% | 26.21 | 406 / 406 |
| pancreas | 100% | 3825.27 | 328 / 328 | 100% | 37.82 | 178 / 178 |
| esophagus | 100% | 3368.65 | 1444 / 1445 | 100% | 19.47 | 183 / 183 |
| thymus | 100% | 8306.53 | 653 / 653 | 100% | 40.62 | 604 / 605 |
| uterus | 100% | 4797.59 | 170 / 170 | 100% | 30.50 | 458 / 459 |
| intestine | 100% | 4577.99 | 966 / 966 | 100% | 31.69 | 525 / 527 |
| kidney | 100% | 6425.53 | 89 / 89 | 100% | 39.72 | 897 / 901 |
| bladder | 100% | 3720.00 | 21 / 21 | 99% | 31.72 | 501 / 504 |
| prostate | 100% | 5995.39 | 245 / 245 | 99% | 25.66 | 499 / 502 |
| lung | 100% | 4378.19 | 578 / 578 | 99% | 22.73 | 1148 / 1155 |
| stomach | 100% | 3749.25 | 359 / 359 | 99% | 26.38 | 284 / 286 |
| adrenal gland | 100% | 4329.84 | 258 / 258 | 99% | 23.33 | 228 / 230 |
| brain | 99% | 3217.62 | 2621 / 2642 | 100% | 24.46 | 704 / 705 |
| breast | 100% | 3874.16 | 459 / 459 | 97% | 17.36 | 1090 / 1118 |
| skin | 100% | 3415.17 | 1809 / 1809 | 97% | 17.88 | 458 / 472 |
| ovary | 100% | 4323.93 | 180 / 180 | 97% | 15.97 | 416 / 430 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 28.81 | 29 / 29 |
| spleen | 100% | 6270.11 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 50.99 | 1 / 1 |
| adipose | 100% | 3114.60 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 2267.90 | 1325 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 1794.41 | 852 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 19.65 | 44 / 45 |
| eye | 0% | 0 | 0 / 0 | 98% | 17.89 | 78 / 80 |
| muscle | 92% | 1272.81 | 735 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 85% | 1673.66 | 792 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0018107 | Biological process | peptidyl-threonine phosphorylation |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_1902018 | Biological process | negative regulation of cilium assembly |
| GO_0007089 | Biological process | traversing start control point of mitotic cell cycle |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0030030 | Biological process | cell projection organization |
| GO_0007346 | Biological process | regulation of mitotic cell cycle |
| GO_0032956 | Biological process | regulation of actin cytoskeleton organization |
| GO_0036064 | Cellular component | ciliary basal body |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0004693 | Molecular function | cyclin-dependent protein serine/threonine kinase activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | CDK10 |
| Protein name | Cyclin dependent kinase 10 (Cyclin-dependent kinase related protein) Cyclin dependent kinase 10 Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10) (Serine/threonine-protein kinase PISSLRE) |
| Synonyms | |
| Description | FUNCTION: Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) . Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling . . |
| Accessions | ENST00000564192.5 ENST00000565470.1 ENST00000625631.1 ENST00000331006.12 F8W872 D6RA59 H3BT74 ENST00000512912.5 ENST00000353379.12 [Q15131-1] Q15131 Q9UHL7 ENST00000508723.5 ENST00000617879.1 [Q15131-4] D6REZ2 D6RHH3 ENST00000502547.5 H3BSN8 ENST00000511415.5 ENST00000510811.6 ENST00000505473.5 [Q15131-4] |
