GRM4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007196Biological processadenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
GO_0007268Biological processchemical synaptic transmission
GO_0007216Biological processG protein-coupled glutamate receptor signaling pathway
GO_0043410Biological processpositive regulation of MAPK cascade
GO_0043523Biological processregulation of neuron apoptotic process
GO_0051966Biological processregulation of synaptic transmission, glutamatergic
GO_0007269Biological processneurotransmitter secretion
GO_0098793Cellular componentpresynapse
GO_0005886Cellular componentplasma membrane
GO_0031410Cellular componentcytoplasmic vesicle
GO_0008066Molecular functionglutamate receptor activity
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0001640Molecular functionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

IV. Literature review

[source]
Gene nameGRM4
Protein nameMetabotropic glutamate receptor 4 (mGluR4)
Glutamate metabotropic receptor 4
Glutamate metabotropic receptor 4 (Glutamate receptor, metabotropic 4)
SynonymsGPRC1D
MGLUR4
hCG_41255
DescriptionFUNCTION: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. .

AccessionsENST00000374177.7 [Q14833-5]
ENST00000374181.8
ENST00000544773.6 [Q14833-3]
V9GYB0
ENST00000609443.1
ENST00000538487.7 [Q14833-1]
V9GYR3
Q14833
ENST00000609278.1
ENST00000535756.5 [Q14833-4]
A1L4F9
ENST00000609222.5 [Q14833-4]
B7ZLU9
ENST00000455714.6 [Q14833-2]