Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 4 studies | 35% ± 15% | |
granule cell | 3 studies | 50% ± 22% | |
GABAergic neuron | 3 studies | 32% ± 10% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 95% | 12621.84 | 2507 / 2642 | 13% | 0.31 | 89 / 705 |
pancreas | 64% | 85.85 | 211 / 328 | 17% | 0.57 | 30 / 178 |
thymus | 9% | 9.42 | 56 / 653 | 40% | 1.78 | 245 / 605 |
breast | 13% | 15.64 | 60 / 459 | 34% | 1.96 | 380 / 1118 |
uterus | 36% | 46.58 | 61 / 170 | 11% | 0.28 | 49 / 459 |
ovary | 3% | 13.41 | 6 / 180 | 28% | 0.77 | 120 / 430 |
prostate | 13% | 12.40 | 31 / 245 | 1% | 0.01 | 5 / 502 |
lung | 3% | 2.24 | 18 / 578 | 9% | 0.34 | 103 / 1155 |
esophagus | 1% | 1.72 | 14 / 1445 | 10% | 0.19 | 18 / 183 |
intestine | 3% | 2.51 | 31 / 966 | 5% | 0.13 | 25 / 527 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.40 | 2 / 29 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.21 | 3 / 45 |
adrenal gland | 1% | 36.38 | 2 / 258 | 5% | 0.44 | 12 / 230 |
stomach | 1% | 1.20 | 5 / 359 | 2% | 0.09 | 7 / 286 |
bladder | 0% | 0 | 0 / 21 | 4% | 0.14 | 18 / 504 |
liver | 2% | 3.19 | 5 / 226 | 1% | 0.03 | 4 / 406 |
skin | 2% | 1.99 | 42 / 1809 | 1% | 0.02 | 3 / 472 |
eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
kidney | 0% | 0 | 0 / 89 | 1% | 0.05 | 9 / 901 |
muscle | 1% | 1.10 | 8 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 0.79 | 9 / 929 | 0% | 0 | 0 / 0 |
spleen | 1% | 0.79 | 2 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 1% | 0.94 | 7 / 1335 | 0% | 0 | 0 / 0 |
heart | 0% | 0.86 | 4 / 861 | 0% | 0 | 0 / 0 |
adipose | 0% | 0.21 | 2 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007196 | Biological process | adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0007216 | Biological process | G protein-coupled glutamate receptor signaling pathway |
GO_0043410 | Biological process | positive regulation of MAPK cascade |
GO_0043523 | Biological process | regulation of neuron apoptotic process |
GO_0051966 | Biological process | regulation of synaptic transmission, glutamatergic |
GO_0007269 | Biological process | neurotransmitter secretion |
GO_0098793 | Cellular component | presynapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0008066 | Molecular function | glutamate receptor activity |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0001640 | Molecular function | adenylate cyclase inhibiting G protein-coupled glutamate receptor activity |
Gene name | GRM4 |
Protein name | Metabotropic glutamate receptor 4 (mGluR4) Glutamate metabotropic receptor 4 Glutamate metabotropic receptor 4 (Glutamate receptor, metabotropic 4) |
Synonyms | GPRC1D MGLUR4 hCG_41255 |
Description | FUNCTION: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. . |
Accessions | ENST00000374177.7 [Q14833-5] ENST00000374181.8 ENST00000544773.6 [Q14833-3] V9GYB0 ENST00000609443.1 ENST00000538487.7 [Q14833-1] V9GYR3 Q14833 ENST00000609278.1 ENST00000535756.5 [Q14833-4] A1L4F9 ENST00000609222.5 [Q14833-4] B7ZLU9 ENST00000455714.6 [Q14833-2] |