ADRA2C report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ADRA2C at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADRA2C at tissue level.

III. Associated gene sets

GO_0071880Biological processadenylate cyclase-activating adrenergic receptor signaling pathway
GO_0032148Biological processactivation of protein kinase B activity
GO_0019229Biological processregulation of vasoconstriction
GO_0006940Biological processregulation of smooth muscle contraction
GO_0035624Biological processreceptor transactivation
GO_0043410Biological processpositive regulation of MAPK cascade
GO_0007267Biological processcell-cell signaling
GO_0030168Biological processplatelet activation
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0045666Biological processpositive regulation of neuron differentiation
GO_0071875Biological processadrenergic receptor signaling pathway
GO_0032811Biological processnegative regulation of epinephrine secretion
GO_0010700Biological processnegative regulation of norepinephrine secretion
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005768Cellular componentendosome
GO_0042803Molecular functionprotein homodimerization activity
GO_0051379Molecular functionepinephrine binding
GO_0031694Molecular functionalpha-2A adrenergic receptor binding
GO_0046982Molecular functionprotein heterodimerization activity
GO_0004938Molecular functionalpha2-adrenergic receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADRA2C
Protein nameAlpha-2C adrenergic receptor (Alpha-2C adrenoreceptor)
Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR)
SynonymsADRA2RL2
ADRA2L2
DescriptionFUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.

FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. .

FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. .

AccessionsQ4W594
P18825
D6RGL0
ENST00000330055.7
ENST00000509482.1