Insufficient scRNA-seq data for expression of ADRA2C at single-cell level.
Insufficient scRNA-seq data for expression of ADRA2C at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 94% | 2357.78 | 230 / 245 | 81% | 11.10 | 408 / 502 |
uterus | 99% | 5092.62 | 168 / 170 | 56% | 14.64 | 259 / 459 |
kidney | 96% | 2108.39 | 85 / 89 | 57% | 7.48 | 517 / 901 |
ovary | 40% | 723.19 | 72 / 180 | 96% | 64.61 | 412 / 430 |
breast | 89% | 819.34 | 408 / 459 | 43% | 6.01 | 477 / 1118 |
skin | 56% | 411.30 | 1020 / 1809 | 51% | 16.96 | 242 / 472 |
pancreas | 29% | 115.68 | 94 / 328 | 72% | 9.17 | 129 / 178 |
blood vessel | 100% | 7068.45 | 1331 / 1335 | 0% | 0 | 0 / 0 |
spleen | 98% | 2212.08 | 235 / 241 | 0% | 0 | 0 / 0 |
lung | 66% | 368.48 | 382 / 578 | 31% | 4.92 | 355 / 1155 |
adipose | 94% | 1477.46 | 1134 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 89% | 21.54 | 71 / 80 |
brain | 66% | 691.09 | 1731 / 2642 | 20% | 1.42 | 138 / 705 |
bladder | 52% | 332.81 | 11 / 21 | 31% | 6.84 | 157 / 504 |
adrenal gland | 47% | 263.74 | 122 / 258 | 33% | 7.13 | 76 / 230 |
esophagus | 32% | 168.94 | 456 / 1445 | 45% | 5.85 | 83 / 183 |
intestine | 34% | 201.69 | 329 / 966 | 43% | 6.84 | 224 / 527 |
stomach | 25% | 146.74 | 90 / 359 | 39% | 8.75 | 111 / 286 |
thymus | 12% | 70.23 | 77 / 653 | 38% | 7.34 | 230 / 605 |
heart | 48% | 213.82 | 410 / 861 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 40% | 10.31 | 161 / 406 |
muscle | 27% | 107.51 | 218 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 20% | 1.48 | 9 / 45 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.16 | 1 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0071880 | Biological process | adenylate cyclase-activating adrenergic receptor signaling pathway |
GO_0032148 | Biological process | activation of protein kinase B activity |
GO_0019229 | Biological process | regulation of vasoconstriction |
GO_0006940 | Biological process | regulation of smooth muscle contraction |
GO_0035624 | Biological process | receptor transactivation |
GO_0043410 | Biological process | positive regulation of MAPK cascade |
GO_0007267 | Biological process | cell-cell signaling |
GO_0030168 | Biological process | platelet activation |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0045666 | Biological process | positive regulation of neuron differentiation |
GO_0071875 | Biological process | adrenergic receptor signaling pathway |
GO_0032811 | Biological process | negative regulation of epinephrine secretion |
GO_0010700 | Biological process | negative regulation of norepinephrine secretion |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005768 | Cellular component | endosome |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0051379 | Molecular function | epinephrine binding |
GO_0031694 | Molecular function | alpha-2A adrenergic receptor binding |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0004938 | Molecular function | alpha2-adrenergic receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ADRA2C |
Protein name | Alpha-2C adrenergic receptor (Alpha-2C adrenoreceptor) Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR) |
Synonyms | ADRA2RL2 ADRA2L2 |
Description | FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. . FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. . |
Accessions | Q4W594 P18825 D6RGL0 ENST00000330055.7 ENST00000509482.1 |