Insufficient scRNA-seq data for expression of EPGN at single-cell level.
Insufficient scRNA-seq data for expression of EPGN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 80% | 112.24 | 1443 / 1809 | 9% | 0.96 | 42 / 472 |
esophagus | 40% | 444.97 | 576 / 1445 | 44% | 8.43 | 81 / 183 |
lung | 30% | 18.67 | 172 / 578 | 31% | 3.07 | 353 / 1155 |
tonsil | 0% | 0 | 0 / 0 | 49% | 6.73 | 22 / 45 |
uterus | 2% | 8.98 | 4 / 170 | 36% | 5.48 | 167 / 459 |
bladder | 0% | 0 | 0 / 21 | 28% | 3.59 | 141 / 504 |
adipose | 21% | 29.58 | 253 / 1204 | 0% | 0 | 0 / 0 |
breast | 4% | 0.80 | 17 / 459 | 16% | 0.72 | 179 / 1118 |
prostate | 14% | 5.31 | 35 / 245 | 4% | 0.08 | 20 / 502 |
ovary | 5% | 1.53 | 9 / 180 | 8% | 0.23 | 36 / 430 |
heart | 10% | 12.31 | 90 / 861 | 0% | 0 | 0 / 0 |
thymus | 2% | 0.49 | 12 / 653 | 6% | 0.22 | 35 / 605 |
liver | 6% | 1.07 | 13 / 226 | 1% | 0.01 | 3 / 406 |
intestine | 2% | 0.55 | 22 / 966 | 4% | 0.53 | 22 / 527 |
spleen | 5% | 1.40 | 13 / 241 | 0% | 0 | 0 / 0 |
pancreas | 1% | 0.24 | 3 / 328 | 3% | 0.12 | 6 / 178 |
blood vessel | 4% | 4.75 | 49 / 1335 | 0% | 0 | 0 / 0 |
stomach | 1% | 1.31 | 4 / 359 | 2% | 0.06 | 7 / 286 |
adrenal gland | 0% | 0.06 | 1 / 258 | 2% | 0.37 | 4 / 230 |
kidney | 1% | 0.21 | 1 / 89 | 1% | 0.08 | 7 / 901 |
peripheral blood | 1% | 0.92 | 9 / 929 | 0% | 0 | 0 / 0 |
muscle | 0% | 0.07 | 2 / 803 | 0% | 0 | 0 / 0 |
brain | 0% | 0.03 | 4 / 2642 | 0% | 0 | 0 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007173 | Biological process | epidermal growth factor receptor signaling pathway |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0001525 | Biological process | angiogenesis |
GO_0050679 | Biological process | positive regulation of epithelial cell proliferation |
GO_0045840 | Biological process | positive regulation of mitotic nuclear division |
GO_0043410 | Biological process | positive regulation of MAPK cascade |
GO_0000165 | Biological process | MAPK cascade |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0030669 | Cellular component | clathrin-coated endocytic vesicle membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005154 | Molecular function | epidermal growth factor receptor binding |
GO_0030297 | Molecular function | transmembrane receptor protein tyrosine kinase activator activity |
GO_0005515 | Molecular function | protein binding |
GO_0008083 | Molecular function | growth factor activity |
Gene name | EPGN |
Protein name | EPGN protein (Epithelial mitogen) Epigen (Epithelial mitogen) (EPG) Epithelial mitogen |
Synonyms | UNQ3072/PRO9904 |
Description | FUNCTION: Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. . |
Accessions | ENST00000502835.5 ENST00000509145.5 [Q6UW88-7] ENST00000446430.2 ENST00000503098.5 [Q6UW88-3] Q6UW88 ENST00000413830.6 [Q6UW88-1] A0PK19 H3BM13 ENST00000505212.5 [Q6UW88-6] ENST00000502358.5 [Q6UW88-4] ENST00000332112.8 [Q6UW88-2] ENST00000514968.5 [Q6UW88-5] |