Insufficient scRNA-seq data for expression of FGF22 at single-cell level.
Insufficient scRNA-seq data for expression of FGF22 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 182.67 | 2621 / 2642 | 34% | 0.68 | 237 / 705 |
prostate | 85% | 67.34 | 209 / 245 | 27% | 0.46 | 138 / 502 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.55 | 1 / 1 |
ovary | 96% | 164.72 | 173 / 180 | 0% | 0.06 | 2 / 430 |
skin | 71% | 493.14 | 1282 / 1809 | 9% | 0.17 | 41 / 472 |
uterus | 72% | 57.65 | 123 / 170 | 6% | 0.12 | 27 / 459 |
bladder | 67% | 53.48 | 14 / 21 | 8% | 0.18 | 38 / 504 |
blood vessel | 69% | 53.13 | 926 / 1335 | 0% | 0 | 0 / 0 |
esophagus | 62% | 43.28 | 890 / 1445 | 2% | 0.03 | 4 / 183 |
breast | 56% | 33.40 | 255 / 459 | 3% | 0.04 | 28 / 1118 |
stomach | 41% | 23.65 | 147 / 359 | 1% | 0.01 | 2 / 286 |
intestine | 38% | 20.16 | 368 / 966 | 1% | 0.05 | 5 / 527 |
adipose | 34% | 18.20 | 409 / 1204 | 0% | 0 | 0 / 0 |
lung | 28% | 14.36 | 161 / 578 | 0% | 0.01 | 5 / 1155 |
adrenal gland | 6% | 2.36 | 16 / 258 | 17% | 0.31 | 38 / 230 |
spleen | 19% | 7.29 | 46 / 241 | 0% | 0 | 0 / 0 |
thymus | 11% | 5.09 | 75 / 653 | 1% | 0.02 | 8 / 605 |
kidney | 11% | 4.96 | 10 / 89 | 1% | 0.02 | 6 / 901 |
liver | 4% | 1.63 | 9 / 226 | 6% | 0.08 | 23 / 406 |
eye | 0% | 0 | 0 / 0 | 9% | 0.13 | 7 / 80 |
muscle | 7% | 2.94 | 60 / 803 | 0% | 0 | 0 / 0 |
heart | 7% | 2.45 | 56 / 861 | 0% | 0 | 0 / 0 |
pancreas | 2% | 0.59 | 6 / 328 | 2% | 0.03 | 3 / 178 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.08 | 1 / 29 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.02 | 1 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0008543 | Biological process | fibroblast growth factor receptor signaling pathway |
GO_0030154 | Biological process | cell differentiation |
GO_0001934 | Biological process | positive regulation of protein phosphorylation |
GO_0030334 | Biological process | regulation of cell migration |
GO_0043410 | Biological process | positive regulation of MAPK cascade |
GO_0009887 | Biological process | animal organ morphogenesis |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005737 | Cellular component | cytoplasm |
GO_0005104 | Molecular function | fibroblast growth factor receptor binding |
GO_0008083 | Molecular function | growth factor activity |
Gene name | FGF22 |
Protein name | Fibroblast growth factor (FGF) Fibroblast growth factor 22 (FGF-22) |
Synonyms | UNQ2500/PRO5800 hCG_20567 |
Description | FUNCTION: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. . |
Accessions | ENST00000215530.7 Q9HCT0 K7ELB9 ENST00000586042.6 O60371 |