ADRA1B | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADRA1B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	498.41	226 / 226	78%	4.30	317 / 406
ovary	88%	224.84	159 / 180	83%	7.18	356 / 430
kidney	92%	178.83	82 / 89	77%	8.44	690 / 901
brain	71%	245.98	1885 / 2642	88%	5.02	618 / 705
thymus	76%	133.15	495 / 653	82%	5.40	494 / 605
adrenal gland	80%	139.57	207 / 258	68%	4.41	157 / 230
lung	90%	351.21	520 / 578	33%	1.21	386 / 1155
breast	77%	161.15	352 / 459	38%	1.39	422 / 1118
skin	55%	110.50	992 / 1809	52%	2.91	246 / 472
spleen	99%	973.59	239 / 241	0%	0	0 / 0
blood vessel	97%	903.63	1298 / 1335	0%	0	0 / 0
adipose	95%	265.30	1141 / 1204	0%	0	0 / 0
uterus	59%	111.95	101 / 170	24%	0.86	111 / 459
heart	74%	96.09	637 / 861	0%	0	0 / 0
esophagus	40%	48.49	577 / 1445	19%	0.57	35 / 183
intestine	46%	51.62	441 / 966	11%	0.62	57 / 527
pancreas	4%	2.99	14 / 328	40%	1.73	71 / 178
stomach	31%	28.15	110 / 359	8%	0.19	24 / 286
prostate	30%	36.72	73 / 245	7%	0.10	34 / 502
tonsil	0%	0	0 / 0	24%	1.26	11 / 45
bladder	14%	9.71	3 / 21	10%	0.53	51 / 504
lymph node	0%	0	0 / 0	24%	2.04	7 / 29
eye	0%	0	0 / 0	16%	0.26	13 / 80
muscle	5%	4.82	44 / 803	0%	0	0 / 0
peripheral blood	0%	0.22	3 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007188	Biological process	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO_0071880	Biological process	adenylate cyclase-activating adrenergic receptor signaling pathway
GO_0007200	Biological process	phospholipase C-activating G protein-coupled receptor signaling pathway
GO_0019229	Biological process	regulation of vasoconstriction
GO_0043410	Biological process	positive regulation of MAPK cascade
GO_0007267	Biological process	cell-cell signaling
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0035556	Biological process	intracellular signal transduction
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0055117	Biological process	regulation of cardiac muscle contraction
GO_0150099	Biological process	neuron-glial cell signaling
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0031965	Cellular component	nuclear membrane
GO_0005901	Cellular component	caveola
GO_0005634	Cellular component	nucleus
GO_0004937	Molecular function	alpha1-adrenergic receptor activity
GO_0046982	Molecular function	protein heterodimerization activity
GO_0005515	Molecular function	protein binding

Gene name	ADRA1B
Protein name	Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor) Adrenoceptor alpha 1B
Synonyms
Description	FUNCTION: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes. .
Accessions	A0A286YF88 P35368 ENST00000306675.5 ENST00000641205.1

ADRA1B report