RIT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007265Biological processRas protein signal transduction
GO_0010976Biological processpositive regulation of neuron projection development
GO_0000165Biological processMAPK cascade
GO_0032489Biological processregulation of Cdc42 protein signal transduction
GO_0001932Biological processregulation of protein phosphorylation
GO_0043410Biological processpositive regulation of MAPK cascade
GO_0035556Biological processintracellular signal transduction
GO_0010977Biological processnegative regulation of neuron projection development
GO_0050848Biological processregulation of calcium-mediated signaling
GO_0007268Biological processchemical synaptic transmission
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0030100Biological processregulation of endocytosis
GO_0032507Biological processmaintenance of protein location in cell
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0097447Cellular componentdendritic tree
GO_0005886Cellular componentplasma membrane
GO_0045121Cellular componentmembrane raft
GO_0005654Cellular componentnucleoplasm
GO_0005794Cellular componentGolgi apparatus
GO_0043005Cellular componentneuron projection
GO_0005829Cellular componentcytosol
GO_0045202Cellular componentsynapse
GO_0005737Cellular componentcytoplasm
GO_0044297Cellular componentcell body
GO_0005634Cellular componentnucleus
GO_0019003Molecular functionGDP binding
GO_0003682Molecular functionchromatin binding
GO_0042802Molecular functionidentical protein binding
GO_0003925Molecular functionG protein activity
GO_0030215Molecular functionsemaphorin receptor binding
GO_0005525Molecular functionGTP binding
GO_0005516Molecular functioncalmodulin binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRIT2
Protein nameGTP-binding protein Rit2 (EC 3.6.5.2) (Ras-like protein expressed in neurons) (Ras-like without CAAX protein 2)
Ras like without CAAX 2
SynonymsROC2
RIN
DescriptionFUNCTION: Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator. .

AccessionsENST00000589109.5 [Q99578-2]
ENST00000590910.1
A0A3B3ITB4
ENST00000326695.10 [Q99578-1]
Q99578
ENST00000650392.1
K7EMR8