ADRA2B | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADRA2B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	90%	328.28	233 / 258	82%	5.41	189 / 230
kidney	96%	605.09	85 / 89	68%	4.15	612 / 901
ovary	84%	270.40	151 / 180	70%	3.99	301 / 430
liver	94%	605.15	213 / 226	54%	1.17	220 / 406
uterus	96%	468.54	164 / 170	39%	1.75	181 / 459
breast	98%	530.76	450 / 459	32%	0.83	354 / 1118
thymus	86%	236.66	560 / 653	42%	0.86	255 / 605
bladder	95%	408.10	20 / 21	28%	0.96	141 / 504
intestine	97%	399.57	937 / 966	24%	0.58	129 / 527
esophagus	77%	436.29	1108 / 1445	41%	1.28	75 / 183
stomach	89%	291.97	321 / 359	26%	0.58	73 / 286
prostate	85%	247.60	209 / 245	19%	0.32	95 / 502
adipose	100%	970.76	1202 / 1204	0%	0	0 / 0
muscle	100%	618.94	801 / 803	0%	0	0 / 0
spleen	100%	1433.48	240 / 241	0%	0	0 / 0
skin	64%	198.66	1158 / 1809	29%	1.61	137 / 472
heart	92%	565.06	792 / 861	0%	0	0 / 0
pancreas	27%	41.91	88 / 328	60%	1.23	107 / 178
blood vessel	85%	905.26	1141 / 1335	0%	0	0 / 0
lung	37%	61.29	214 / 578	37%	2.66	422 / 1155
brain	43%	114.91	1128 / 2642	30%	0.77	211 / 705
tonsil	0%	0	0 / 0	38%	1.81	17 / 45
eye	0%	0	0 / 0	16%	0.24	13 / 80
lymph node	0%	0	0 / 0	7%	0.11	2 / 29
peripheral blood	1%	1.28	8 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001525	Biological process	angiogenesis
GO_0071880	Biological process	adenylate cyclase-activating adrenergic receptor signaling pathway
GO_0032148	Biological process	activation of protein kinase B activity
GO_0045777	Biological process	positive regulation of blood pressure
GO_0000165	Biological process	MAPK cascade
GO_0035624	Biological process	receptor transactivation
GO_0043410	Biological process	positive regulation of MAPK cascade
GO_0007565	Biological process	female pregnancy
GO_0007267	Biological process	cell-cell signaling
GO_0030168	Biological process	platelet activation
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0070474	Biological process	positive regulation of uterine smooth muscle contraction
GO_0003056	Biological process	regulation of vascular associated smooth muscle contraction
GO_0045666	Biological process	positive regulation of neuron differentiation
GO_0071875	Biological process	adrenergic receptor signaling pathway
GO_0032811	Biological process	negative regulation of epinephrine secretion
GO_0010700	Biological process	negative regulation of norepinephrine secretion
GO_0005886	Cellular component	plasma membrane
GO_0009986	Cellular component	cell surface
GO_0005829	Cellular component	cytosol
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0051379	Molecular function	epinephrine binding
GO_0004938	Molecular function	alpha2-adrenergic receptor activity
GO_0005515	Molecular function	protein binding

Gene name	ADRA2B
Protein name	Alternative protein ADRA2B Alpha-2B adrenergic receptor (Alpha-2 adrenergic receptor subtype C2) (Alpha-2B adrenoreceptor) (Alpha-2B adrenoceptor) (Alpha-2BAR)
Synonyms	ADRA2RL1 ADRA2L1
Description	FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol. .
Accessions	L8E8D5 P18089 ENST00000620793.2

ADRA2B report