Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pericyte | 22 studies | 26% ± 8% | |
| smooth muscle cell | 19 studies | 24% ± 8% | |
| fibroblast | 15 studies | 26% ± 10% | |
| endothelial cell | 14 studies | 27% ± 10% | |
| capillary endothelial cell | 9 studies | 19% ± 7% | |
| endothelial cell of lymphatic vessel | 9 studies | 22% ± 4% | |
| macrophage | 7 studies | 20% ± 3% | |
| connective tissue cell | 6 studies | 32% ± 9% | |
| epithelial cell | 5 studies | 28% ± 10% | |
| astrocyte | 5 studies | 24% ± 7% | |
| basal cell | 4 studies | 22% ± 6% | |
| myofibroblast cell | 4 studies | 29% ± 10% | |
| oligodendrocyte precursor cell | 4 studies | 25% ± 5% | |
| type I pneumocyte | 3 studies | 21% ± 0% | |
| ciliated cell | 3 studies | 19% ± 3% | |
| abnormal cell | 3 studies | 24% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 4 studies | 20% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 13375.22 | 245 / 245 | 100% | 64.50 | 500 / 502 |
| skin | 100% | 9061.50 | 1805 / 1809 | 99% | 63.40 | 467 / 472 |
| thymus | 100% | 10490.67 | 651 / 653 | 99% | 51.06 | 599 / 605 |
| breast | 100% | 14372.41 | 459 / 459 | 98% | 49.58 | 1092 / 1118 |
| liver | 98% | 5710.86 | 222 / 226 | 99% | 33.34 | 403 / 406 |
| intestine | 100% | 9269.55 | 966 / 966 | 97% | 35.37 | 512 / 527 |
| esophagus | 99% | 9112.01 | 1437 / 1445 | 97% | 31.23 | 177 / 183 |
| lung | 100% | 11943.36 | 577 / 578 | 96% | 34.54 | 1111 / 1155 |
| ovary | 100% | 11603.35 | 180 / 180 | 96% | 33.84 | 411 / 430 |
| brain | 95% | 4725.59 | 2500 / 2642 | 100% | 70.53 | 705 / 705 |
| adrenal gland | 100% | 6106.07 | 258 / 258 | 94% | 63.16 | 217 / 230 |
| uterus | 100% | 14885.30 | 170 / 170 | 94% | 44.00 | 433 / 459 |
| kidney | 99% | 7200.91 | 88 / 89 | 95% | 50.57 | 855 / 901 |
| bladder | 100% | 10700.38 | 21 / 21 | 89% | 30.35 | 450 / 504 |
| stomach | 88% | 5131.31 | 315 / 359 | 96% | 33.37 | 274 / 286 |
| pancreas | 71% | 2387.70 | 233 / 328 | 98% | 47.20 | 175 / 178 |
| adipose | 100% | 17143.48 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 23496.08 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 105.60 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 24.33 | 29 / 29 |
| spleen | 100% | 8381.11 | 241 / 241 | 0% | 0 | 0 / 0 |
| heart | 99% | 6497.55 | 851 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 40.02 | 44 / 45 |
| muscle | 90% | 4414.25 | 725 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 5% | 142.98 | 49 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0031589 | Biological process | cell-substrate adhesion |
| GO_0051495 | Biological process | positive regulation of cytoskeleton organization |
| GO_0007155 | Biological process | cell adhesion |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0000165 | Biological process | MAPK cascade |
| GO_0051496 | Biological process | positive regulation of stress fiber assembly |
| GO_0030055 | Cellular component | cell-substrate junction |
| GO_0005829 | Cellular component | cytosol |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0017166 | Molecular function | vinculin binding |
| GO_0005200 | Molecular function | structural constituent of cytoskeleton |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SORBS3 |
| Protein name | SORBS3 protein Sorbin and SH3 domain containing 3 Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3) |
| Synonyms | SCAM1 |
| Description | FUNCTION: Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain. |
| Accessions | ENST00000240123.12 [O60504-1] H0YAZ3 ENST00000523900.5 E5RIA0 ENST00000517962.1 O60504 ENST00000522721.1 H0YB51 ENST00000523348.1 ENST00000523965.5 [O60504-2] E5RJP2 ENST00000520563.3 Q9BT70 ENST00000517500.5 E7EQH0 H0YAU6 |