SORBS3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031589Biological processcell-substrate adhesion
GO_0051495Biological processpositive regulation of cytoskeleton organization
GO_0007155Biological processcell adhesion
GO_0007010Biological processcytoskeleton organization
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0043410Biological processpositive regulation of MAPK cascade
GO_0000165Biological processMAPK cascade
GO_0051496Biological processpositive regulation of stress fiber assembly
GO_0030055Cellular componentcell-substrate junction
GO_0005829Cellular componentcytosol
GO_0005856Cellular componentcytoskeleton
GO_0005925Cellular componentfocal adhesion
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0017166Molecular functionvinculin binding
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSORBS3
Protein nameSORBS3 protein
Sorbin and SH3 domain containing 3
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)
SynonymsSCAM1
DescriptionFUNCTION: Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain.

AccessionsENST00000240123.12 [O60504-1]
H0YAZ3
ENST00000523900.5
E5RIA0
ENST00000517962.1
O60504
ENST00000522721.1
H0YB51
ENST00000523348.1
ENST00000523965.5 [O60504-2]
E5RJP2
ENST00000520563.3
Q9BT70
ENST00000517500.5
E7EQH0
H0YAU6