Insufficient scRNA-seq data for expression of DRD5 at single-cell level.
Insufficient scRNA-seq data for expression of DRD5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 70% | 104.52 | 1848 / 2642 | 18% | 0.51 | 128 / 705 |
prostate | 55% | 22.13 | 134 / 245 | 1% | 0.01 | 4 / 502 |
ovary | 11% | 2.32 | 19 / 180 | 8% | 0.18 | 33 / 430 |
adrenal gland | 1% | 0.73 | 2 / 258 | 17% | 2.49 | 40 / 230 |
lung | 8% | 1.46 | 45 / 578 | 7% | 0.22 | 84 / 1155 |
intestine | 10% | 4.25 | 92 / 966 | 6% | 0.23 | 29 / 527 |
esophagus | 3% | 0.57 | 48 / 1445 | 7% | 0.15 | 13 / 183 |
tonsil | 0% | 0 | 0 / 0 | 9% | 0.26 | 4 / 45 |
uterus | 2% | 0.69 | 4 / 170 | 5% | 0.19 | 24 / 459 |
kidney | 7% | 1.85 | 6 / 89 | 0% | 0.00 | 1 / 901 |
blood vessel | 5% | 3.66 | 63 / 1335 | 0% | 0 | 0 / 0 |
bladder | 0% | 0 | 0 / 21 | 4% | 0.09 | 21 / 504 |
heart | 3% | 0.74 | 27 / 861 | 0% | 0 | 0 / 0 |
skin | 2% | 0.80 | 42 / 1809 | 0% | 0 | 0 / 472 |
liver | 1% | 0.16 | 3 / 226 | 0% | 0.01 | 2 / 406 |
eye | 0% | 0 | 0 / 0 | 1% | 0.06 | 1 / 80 |
breast | 1% | 0.15 | 4 / 459 | 0% | 0.01 | 4 / 1118 |
thymus | 1% | 0.14 | 4 / 653 | 0% | 0.02 | 2 / 605 |
stomach | 0% | 0 | 0 / 359 | 1% | 0.01 | 2 / 286 |
pancreas | 0% | 0 | 0 / 328 | 1% | 0.01 | 1 / 178 |
adipose | 0% | 0.09 | 6 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.03 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0045762 | Biological process | positive regulation of adenylate cyclase activity |
GO_0045924 | Biological process | regulation of female receptivity |
GO_0071880 | Biological process | adenylate cyclase-activating adrenergic receptor signaling pathway |
GO_0007191 | Biological process | adenylate cyclase-activating dopamine receptor signaling pathway |
GO_0008306 | Biological process | associative learning |
GO_0006874 | Biological process | intracellular calcium ion homeostasis |
GO_0060158 | Biological process | phospholipase C-activating dopamine receptor signaling pathway |
GO_0043410 | Biological process | positive regulation of MAPK cascade |
GO_0060292 | Biological process | long-term synaptic depression |
GO_0001992 | Biological process | regulation of systemic arterial blood pressure by vasopressin |
GO_0072593 | Biological process | reactive oxygen species metabolic process |
GO_0042060 | Biological process | wound healing |
GO_0042220 | Biological process | response to cocaine |
GO_0007190 | Biological process | activation of adenylate cyclase activity |
GO_0071870 | Biological process | cellular response to catecholamine stimulus |
GO_0045776 | Biological process | negative regulation of blood pressure |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0001963 | Biological process | synaptic transmission, dopaminergic |
GO_0001975 | Biological process | response to amphetamine |
GO_0019226 | Biological process | transmission of nerve impulse |
GO_0046960 | Biological process | sensitization |
GO_0007212 | Biological process | G protein-coupled dopamine receptor signaling pathway |
GO_0033861 | Biological process | negative regulation of NAD(P)H oxidase activity |
GO_0001994 | Biological process | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure |
GO_0031526 | Cellular component | brush border membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0060170 | Cellular component | ciliary membrane |
GO_0005929 | Cellular component | cilium |
GO_0097730 | Cellular component | non-motile cilium |
GO_0045202 | Cellular component | synapse |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0004952 | Molecular function | dopamine neurotransmitter receptor activity |
GO_0001588 | Molecular function | dopamine neurotransmitter receptor activity, coupled via Gs |
GO_0035240 | Molecular function | dopamine binding |
GO_0005515 | Molecular function | protein binding |
Gene name | DRD5 |
Protein name | D(1B) dopamine receptor (D(5) dopamine receptor) (D1beta dopamine receptor) (Dopamine D5 receptor) |
Synonyms | DRD1L2 DRD1B |
Description | FUNCTION: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. . |
Accessions | ENST00000304374.4 P21918 |