DRD5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DRD5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DRD5 at tissue level.

III. Associated gene sets

GO_0045762Biological processpositive regulation of adenylate cyclase activity
GO_0045924Biological processregulation of female receptivity
GO_0071880Biological processadenylate cyclase-activating adrenergic receptor signaling pathway
GO_0007191Biological processadenylate cyclase-activating dopamine receptor signaling pathway
GO_0008306Biological processassociative learning
GO_0006874Biological processintracellular calcium ion homeostasis
GO_0060158Biological processphospholipase C-activating dopamine receptor signaling pathway
GO_0043410Biological processpositive regulation of MAPK cascade
GO_0060292Biological processlong-term synaptic depression
GO_0001992Biological processregulation of systemic arterial blood pressure by vasopressin
GO_0072593Biological processreactive oxygen species metabolic process
GO_0042060Biological processwound healing
GO_0042220Biological processresponse to cocaine
GO_0007190Biological processactivation of adenylate cyclase activity
GO_0071870Biological processcellular response to catecholamine stimulus
GO_0045776Biological processnegative regulation of blood pressure
GO_0007268Biological processchemical synaptic transmission
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0001963Biological processsynaptic transmission, dopaminergic
GO_0001975Biological processresponse to amphetamine
GO_0019226Biological processtransmission of nerve impulse
GO_0046960Biological processsensitization
GO_0007212Biological processG protein-coupled dopamine receptor signaling pathway
GO_0033861Biological processnegative regulation of NAD(P)H oxidase activity
GO_0001994Biological processnorepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
GO_0031526Cellular componentbrush border membrane
GO_0005886Cellular componentplasma membrane
GO_0060170Cellular componentciliary membrane
GO_0005929Cellular componentcilium
GO_0097730Cellular componentnon-motile cilium
GO_0045202Cellular componentsynapse
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0004952Molecular functiondopamine neurotransmitter receptor activity
GO_0001588Molecular functiondopamine neurotransmitter receptor activity, coupled via Gs
GO_0035240Molecular functiondopamine binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDRD5
Protein nameD(1B) dopamine receptor (D(5) dopamine receptor) (D1beta dopamine receptor) (Dopamine D5 receptor)
SynonymsDRD1L2
DRD1B
DescriptionFUNCTION: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. .

AccessionsENST00000304374.4
P21918