Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal rod cell | 8 studies | 93% ± 4% | |
| retinal cone cell | 7 studies | 46% ± 20% | |
| amacrine cell | 5 studies | 45% ± 11% | |
| retinal ganglion cell | 4 studies | 41% ± 32% | |
| retinal bipolar neuron | 3 studies | 54% ± 4% | |
| astrocyte | 3 studies | 53% ± 17% | |
| retina horizontal cell | 3 studies | 35% ± 10% | |
| microglial cell | 3 studies | 51% ± 12% | |
| Mueller cell | 3 studies | 50% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| eye | 7 studies | 61% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 78.92 | 89 / 89 | 90% | 5.10 | 812 / 901 |
| lung | 99% | 42.13 | 571 / 578 | 86% | 3.97 | 994 / 1155 |
| skin | 83% | 17.17 | 1496 / 1809 | 91% | 10.01 | 428 / 472 |
| breast | 83% | 18.47 | 381 / 459 | 85% | 2.90 | 953 / 1118 |
| liver | 83% | 20.31 | 188 / 226 | 73% | 2.46 | 296 / 406 |
| thymus | 79% | 15.89 | 517 / 653 | 72% | 4.00 | 436 / 605 |
| adrenal gland | 98% | 38.57 | 253 / 258 | 52% | 3.01 | 119 / 230 |
| bladder | 76% | 13.14 | 16 / 21 | 61% | 2.66 | 306 / 504 |
| stomach | 76% | 12.99 | 274 / 359 | 60% | 1.66 | 172 / 286 |
| intestine | 81% | 30.28 | 778 / 966 | 51% | 1.48 | 270 / 527 |
| prostate | 72% | 12.85 | 177 / 245 | 44% | 0.88 | 219 / 502 |
| uterus | 47% | 5.45 | 80 / 170 | 68% | 3.18 | 312 / 459 |
| brain | 52% | 7.25 | 1374 / 2642 | 59% | 1.43 | 415 / 705 |
| ovary | 22% | 3.04 | 40 / 180 | 87% | 11.68 | 375 / 430 |
| esophagus | 58% | 8.11 | 833 / 1445 | 45% | 0.94 | 82 / 183 |
| eye | 0% | 0 | 0 / 0 | 100% | 82.93 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 36.50 | 29 / 29 |
| spleen | 100% | 408.59 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 100% | 192.02 | 928 / 929 | 0% | 0 | 0 / 0 |
| pancreas | 19% | 2.59 | 63 / 328 | 79% | 3.19 | 140 / 178 |
| adipose | 90% | 22.20 | 1084 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 3.27 | 37 / 45 |
| muscle | 51% | 7.62 | 406 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 49% | 9.81 | 650 / 1335 | 0% | 0 | 0 / 0 |
| heart | 22% | 2.54 | 191 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007601 | Biological process | visual perception |
| GO_0045742 | Biological process | positive regulation of epidermal growth factor receptor signaling pathway |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0045745 | Biological process | positive regulation of G protein-coupled receptor signaling pathway |
| GO_0097381 | Cellular component | photoreceptor disc membrane |
| GO_0042622 | Cellular component | photoreceptor outer segment membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0047555 | Molecular function | 3',5'-cyclic-GMP phosphodiesterase activity |
| GO_0004857 | Molecular function | enzyme inhibitor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0030507 | Molecular function | spectrin binding |
| GO_0030553 | Molecular function | cGMP binding |
| Gene name | PDE6G |
| Protein name | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma) (EC 3.1.4.35) |
| Synonyms | PDEG |
| Description | FUNCTION: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones. |
| Accessions | P18545 ENST00000331056.10 ENST00000571004.1 ENST00000571224.5 |
