Insufficient scRNA-seq data for expression of FGF17 at single-cell level.
Insufficient scRNA-seq data for expression of FGF17 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 97% | 1749.50 | 2552 / 2642 | 66% | 4.02 | 468 / 705 |
adrenal gland | 97% | 413.27 | 251 / 258 | 44% | 3.86 | 102 / 230 |
thymus | 100% | 719.41 | 651 / 653 | 39% | 3.28 | 235 / 605 |
prostate | 91% | 373.20 | 223 / 245 | 24% | 0.45 | 122 / 502 |
ovary | 81% | 163.09 | 145 / 180 | 26% | 8.04 | 113 / 430 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.05 | 1 / 1 |
spleen | 100% | 525.50 | 240 / 241 | 0% | 0 | 0 / 0 |
uterus | 75% | 224.83 | 128 / 170 | 23% | 0.99 | 104 / 459 |
kidney | 83% | 145.27 | 74 / 89 | 7% | 0.13 | 64 / 901 |
pancreas | 54% | 76.51 | 176 / 328 | 11% | 0.28 | 19 / 178 |
bladder | 52% | 57.57 | 11 / 21 | 5% | 0.11 | 23 / 504 |
lung | 44% | 66.46 | 257 / 578 | 6% | 0.21 | 73 / 1155 |
breast | 24% | 30.49 | 109 / 459 | 2% | 0.03 | 18 / 1118 |
blood vessel | 23% | 26.97 | 301 / 1335 | 0% | 0 | 0 / 0 |
stomach | 19% | 21.67 | 67 / 359 | 2% | 0.04 | 7 / 286 |
intestine | 14% | 16.10 | 137 / 966 | 3% | 0.07 | 16 / 527 |
skin | 10% | 10.09 | 173 / 1809 | 7% | 0.19 | 34 / 472 |
liver | 8% | 9.72 | 19 / 226 | 7% | 0.42 | 29 / 406 |
adipose | 15% | 19.47 | 181 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 13% | 0.27 | 6 / 45 |
esophagus | 9% | 10.06 | 126 / 1445 | 3% | 0.05 | 6 / 183 |
eye | 0% | 0 | 0 / 0 | 10% | 0.16 | 8 / 80 |
heart | 8% | 8.19 | 65 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.10 | 2 / 29 |
peripheral blood | 0% | 0.39 | 4 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0008543 | Biological process | fibroblast growth factor receptor signaling pathway |
GO_0030154 | Biological process | cell differentiation |
GO_0001934 | Biological process | positive regulation of protein phosphorylation |
GO_0030334 | Biological process | regulation of cell migration |
GO_0007399 | Biological process | nervous system development |
GO_0043410 | Biological process | positive regulation of MAPK cascade |
GO_0007267 | Biological process | cell-cell signaling |
GO_0009887 | Biological process | animal organ morphogenesis |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005737 | Cellular component | cytoplasm |
GO_0005105 | Molecular function | type 1 fibroblast growth factor receptor binding |
GO_0005111 | Molecular function | type 2 fibroblast growth factor receptor binding |
GO_0005515 | Molecular function | protein binding |
GO_0008083 | Molecular function | growth factor activity |
Gene name | FGF17 |
Protein name | Fibroblast growth factor 17 (FGF-17) Fibroblast growth factor (FGF) |
Synonyms | FGF6B hCG_23792 UNQ161/PRO187 |
Description | FUNCTION: Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development. . |
Accessions | A0A7U3JVY9 ENST00000518533.5 [O60258-2] O60258 ENST00000359441.4 [O60258-1] |