LPAR3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LPAR3 at tissue level.

III. Associated gene sets

GO_0032060Biological processbleb assembly
GO_0010467Biological processgene expression
GO_0048672Biological processpositive regulation of collateral sprouting
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0007268Biological processchemical synaptic transmission
GO_0043410Biological processpositive regulation of MAPK cascade
GO_0048668Biological processcollateral sprouting
GO_0019222Biological processregulation of metabolic process
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0030424Cellular componentaxon
GO_0045202Cellular componentsynapse
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0070915Molecular functionlysophosphatidic acid receptor activity
GO_0005515Molecular functionprotein binding
GO_0008289Molecular functionlipid binding

IV. Literature review

[source]
Gene nameLPAR3
Protein nameLysophosphatidic acid receptor 3 (LPA receptor 3) (LPA-3) (Lysophosphatidic acid receptor Edg-7)
SynonymsLPA3
EDG7
DescriptionFUNCTION: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.

AccessionsQ9UBY5
ENST00000370611.4
ENST00000440886.1