Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 4 studies | 23% ± 5% | |
| epithelial cell | 3 studies | 21% ± 8% |
Insufficient scRNA-seq data for expression of LPAR3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 93% | 1428.50 | 229 / 245 | 91% | 53.74 | 455 / 502 |
| ovary | 59% | 185.39 | 106 / 180 | 95% | 72.48 | 409 / 430 |
| lung | 79% | 213.55 | 457 / 578 | 51% | 12.72 | 587 / 1155 |
| pancreas | 100% | 727.41 | 328 / 328 | 8% | 1.11 | 14 / 178 |
| skin | 85% | 466.36 | 1539 / 1809 | 19% | 3.57 | 90 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.11 | 1 / 1 |
| bladder | 48% | 279.24 | 10 / 21 | 49% | 12.87 | 247 / 504 |
| esophagus | 39% | 366.65 | 563 / 1445 | 55% | 15.23 | 100 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 26.82 | 41 / 45 |
| heart | 89% | 876.48 | 766 / 861 | 0% | 0 | 0 / 0 |
| uterus | 17% | 113.23 | 29 / 170 | 70% | 18.80 | 323 / 459 |
| adrenal gland | 52% | 167.69 | 134 / 258 | 2% | 0.22 | 5 / 230 |
| brain | 53% | 210.56 | 1402 / 2642 | 0% | 0.01 | 1 / 705 |
| breast | 14% | 29.24 | 63 / 459 | 21% | 3.54 | 231 / 1118 |
| intestine | 16% | 30.48 | 157 / 966 | 6% | 0.58 | 29 / 527 |
| thymus | 0% | 0.40 | 2 / 653 | 11% | 2.12 | 66 / 605 |
| liver | 3% | 10.23 | 6 / 226 | 5% | 0.77 | 22 / 406 |
| stomach | 1% | 0.70 | 2 / 359 | 5% | 0.56 | 15 / 286 |
| spleen | 1% | 1.40 | 2 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 2.76 | 10 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 1% | 2.18 | 9 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 1% | 0.49 | 6 / 901 |
| peripheral blood | 0% | 0.58 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032060 | Biological process | bleb assembly |
| GO_0010467 | Biological process | gene expression |
| GO_0048672 | Biological process | positive regulation of collateral sprouting |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0048668 | Biological process | collateral sprouting |
| GO_0019222 | Biological process | regulation of metabolic process |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| GO_0030424 | Cellular component | axon |
| GO_0045202 | Cellular component | synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004930 | Molecular function | G protein-coupled receptor activity |
| GO_0070915 | Molecular function | lysophosphatidic acid receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008289 | Molecular function | lipid binding |
| Gene name | LPAR3 |
| Protein name | Lysophosphatidic acid receptor 3 (LPA receptor 3) (LPA-3) (Lysophosphatidic acid receptor Edg-7) |
| Synonyms | LPA3 EDG7 |
| Description | FUNCTION: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. |
| Accessions | Q9UBY5 ENST00000370611.4 ENST00000440886.1 |