ELK1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ELK1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ELK1 at tissue level.

III. Associated gene sets

GO_0030324Biological processlung development
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0001889Biological processliver development
GO_0071394Biological processcellular response to testosterone stimulus
GO_0045471Biological processresponse to ethanol
GO_0071480Biological processcellular response to gamma radiation
GO_0071774Biological processresponse to fibroblast growth factor
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0110088Biological processhippocampal neuron apoptotic process
GO_0030154Biological processcell differentiation
GO_0009416Biological processresponse to light stimulus
GO_0010467Biological processgene expression
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0031966Cellular componentmitochondrial membrane
GO_0043679Cellular componentaxon terminus
GO_0005654Cellular componentnucleoplasm
GO_0043025Cellular componentneuronal cell body
GO_0030425Cellular componentdendrite
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003682Molecular functionchromatin binding
GO_0000976Molecular functiontranscription cis-regulatory region binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0061629Molecular functionRNA polymerase II-specific DNA-binding transcription factor binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0030374Molecular functionnuclear receptor coactivator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameELK1
Protein nameETS domain-containing protein Elk-1
ELK1 protein
Synonyms
DescriptionFUNCTION: Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2. Induces target gene transcription upon JNK-signaling pathway stimulation (By similarity). .

AccessionsENST00000376983.8 [P19419-1]
Q6FG56
P19419
ENST00000247161.7 [P19419-1]
ENST00000343894.8 [P19419-2]