Insufficient scRNA-seq data for expression of ZIC3 at single-cell level.
Insufficient scRNA-seq data for expression of ZIC3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 98% | 578.30 | 2601 / 2642 | 73% | 2.11 | 518 / 705 |
prostate | 1% | 0.46 | 3 / 245 | 14% | 0.37 | 69 / 502 |
ovary | 2% | 0.68 | 3 / 180 | 7% | 0.62 | 30 / 430 |
adrenal gland | 1% | 6.07 | 2 / 258 | 4% | 0.37 | 10 / 230 |
lung | 0% | 0 | 0 / 578 | 4% | 0.20 | 48 / 1155 |
uterus | 0% | 0 | 0 / 170 | 3% | 0.13 | 15 / 459 |
eye | 0% | 0 | 0 / 0 | 3% | 0.04 | 2 / 80 |
esophagus | 0% | 0.03 | 2 / 1445 | 2% | 0.08 | 4 / 183 |
skin | 0% | 0.07 | 3 / 1809 | 2% | 0.10 | 10 / 472 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.07 | 1 / 45 |
stomach | 1% | 0.33 | 4 / 359 | 1% | 0.01 | 2 / 286 |
breast | 0% | 0 | 0 / 459 | 2% | 0.08 | 20 / 1118 |
kidney | 0% | 0 | 0 / 89 | 2% | 0.09 | 16 / 901 |
adipose | 1% | 0.34 | 10 / 1204 | 0% | 0 | 0 / 0 |
bladder | 0% | 0 | 0 / 21 | 1% | 0.07 | 3 / 504 |
pancreas | 0% | 0 | 0 / 328 | 1% | 0.03 | 1 / 178 |
intestine | 0% | 0 | 0 / 966 | 0% | 0.01 | 1 / 527 |
heart | 0% | 0.03 | 1 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0.04 | 1 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
thymus | 0% | 0 | 0 / 653 | 0% | 0 | 0 / 605 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042473 | Biological process | outer ear morphogenesis |
GO_0071910 | Biological process | determination of liver left/right asymmetry |
GO_1904888 | Biological process | cranial skeletal system development |
GO_0035283 | Biological process | central nervous system segmentation |
GO_0007224 | Biological process | smoothened signaling pathway |
GO_0021766 | Biological process | hippocampus development |
GO_0030324 | Biological process | lung development |
GO_0070986 | Biological process | left/right axis specification |
GO_0007368 | Biological process | determination of left/right symmetry |
GO_0001947 | Biological process | heart looping |
GO_0090009 | Biological process | primitive streak formation |
GO_0001840 | Biological process | neural plate development |
GO_0048339 | Biological process | paraxial mesoderm development |
GO_0035469 | Biological process | determination of pancreatic left/right asymmetry |
GO_0035545 | Biological process | determination of left/right asymmetry in nervous system |
GO_0021772 | Biological process | olfactory bulb development |
GO_0071907 | Biological process | determination of digestive tract left/right asymmetry |
GO_0030182 | Biological process | neuron differentiation |
GO_0009880 | Biological process | embryonic pattern specification |
GO_0003228 | Biological process | atrial cardiac muscle tissue development |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0060324 | Biological process | face development |
GO_0035108 | Biological process | limb morphogenesis |
GO_0042789 | Biological process | mRNA transcription by RNA polymerase II |
GO_0007417 | Biological process | central nervous system development |
GO_0001501 | Biological process | skeletal system development |
GO_0048863 | Biological process | stem cell differentiation |
GO_0048318 | Biological process | axial mesoderm development |
GO_0030718 | Biological process | germ-line stem cell population maintenance |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0043565 | Molecular function | sequence-specific DNA binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0003713 | Molecular function | transcription coactivator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ZIC3 |
Protein name | Zinc finger protein ZIC 3 (Zinc finger protein 203) (Zinc finger protein of the cerebellum 3) |
Synonyms | ZNF203 |
Description | FUNCTION: Acts as a transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. . |
Accessions | ENST00000287538.10 [O60481-1] O60481 ENST00000370606.3 [O60481-2] |