ZIC3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZIC3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZIC3 at tissue level.

III. Associated gene sets

GO_0042473Biological processouter ear morphogenesis
GO_0071910Biological processdetermination of liver left/right asymmetry
GO_1904888Biological processcranial skeletal system development
GO_0035283Biological processcentral nervous system segmentation
GO_0007224Biological processsmoothened signaling pathway
GO_0021766Biological processhippocampus development
GO_0030324Biological processlung development
GO_0070986Biological processleft/right axis specification
GO_0007368Biological processdetermination of left/right symmetry
GO_0001947Biological processheart looping
GO_0090009Biological processprimitive streak formation
GO_0001840Biological processneural plate development
GO_0048339Biological processparaxial mesoderm development
GO_0035469Biological processdetermination of pancreatic left/right asymmetry
GO_0035545Biological processdetermination of left/right asymmetry in nervous system
GO_0021772Biological processolfactory bulb development
GO_0071907Biological processdetermination of digestive tract left/right asymmetry
GO_0030182Biological processneuron differentiation
GO_0009880Biological processembryonic pattern specification
GO_0003228Biological processatrial cardiac muscle tissue development
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0060324Biological processface development
GO_0035108Biological processlimb morphogenesis
GO_0042789Biological processmRNA transcription by RNA polymerase II
GO_0007417Biological processcentral nervous system development
GO_0001501Biological processskeletal system development
GO_0048863Biological processstem cell differentiation
GO_0048318Biological processaxial mesoderm development
GO_0030718Biological processgerm-line stem cell population maintenance
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0046872Molecular functionmetal ion binding
GO_0003713Molecular functiontranscription coactivator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameZIC3
Protein nameZinc finger protein ZIC 3 (Zinc finger protein 203) (Zinc finger protein of the cerebellum 3)
SynonymsZNF203
DescriptionFUNCTION: Acts as a transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. .

AccessionsENST00000287538.10 [O60481-1]
O60481
ENST00000370606.3 [O60481-2]