NDRG4 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
astrocyte	16 studies	29% ± 11%	Explore
glutamatergic neuron	11 studies	49% ± 20%	Explore
GABAergic neuron	8 studies	44% ± 22%	Explore
neuron	7 studies	39% ± 15%	Explore
amacrine cell	7 studies	42% ± 20%	Explore
retina horizontal cell	7 studies	68% ± 24%	Explore
retinal ganglion cell	6 studies	81% ± 22%	Explore
endothelial cell of artery	5 studies	22% ± 4%	Explore
cardiac muscle cell	5 studies	45% ± 15%	Explore
oligodendrocyte precursor cell	5 studies	23% ± 6%	Explore
interneuron	5 studies	45% ± 24%	Explore
endothelial cell	4 studies	34% ± 15%	Explore
GABAergic interneuron	3 studies	31% ± 7%	Explore
GABAergic amacrine cell	3 studies	35% ± 12%	Explore
glycinergic amacrine cell	3 studies	27% ± 11%	Explore
Mueller cell	3 studies	33% ± 7%	Explore
granule cell	3 studies	33% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	13 studies	33% ± 20%	Explore
eye	4 studies	27% ± 9%	Explore
heart	3 studies	20% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	98%	44916.62	2586 / 2642	100%	149.11	702 / 705
adrenal gland	99%	24984.00	255 / 258	93%	216.27	213 / 230
uterus	42%	3066.92	72 / 170	53%	11.76	244 / 459
heart	92%	26191.20	792 / 861	0%	0	0 / 0
lung	41%	2679.39	237 / 578	37%	9.19	430 / 1155
esophagus	15%	806.86	216 / 1445	45%	12.68	82 / 183
spleen	54%	3805.15	131 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	49%	6.86	22 / 45
skin	27%	1614.58	480 / 1809	17%	2.27	82 / 472
ovary	0%	0	0 / 180	37%	3.73	157 / 430
bladder	0%	0	0 / 21	35%	5.40	175 / 504
pancreas	0%	0	0 / 328	34%	4.89	61 / 178
breast	14%	1244.80	62 / 459	15%	1.82	166 / 1118
adipose	18%	1535.16	217 / 1204	0%	0	0 / 0
thymus	0%	0	0 / 653	13%	3.61	81 / 605
kidney	0%	0	0 / 89	11%	2.07	98 / 901
eye	0%	0	0 / 0	9%	2.87	7 / 80
lymph node	0%	0	0 / 0	7%	0.65	2 / 29
intestine	1%	45.05	9 / 966	6%	0.64	29 / 527
stomach	0%	23.04	1 / 359	4%	0.33	12 / 286
liver	0%	0	0 / 226	4%	2.75	18 / 406
prostate	1%	37.93	2 / 245	2%	0.15	9 / 502
blood vessel	2%	227.23	32 / 1335	0%	0	0 / 0
muscle	0%	27.75	4 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0010642	Biological process	negative regulation of platelet-derived growth factor receptor signaling pathway
GO_0014912	Biological process	negative regulation of smooth muscle cell migration
GO_0010976	Biological process	positive regulation of neuron projection development
GO_0001947	Biological process	heart looping
GO_0007165	Biological process	signal transduction
GO_0008542	Biological process	visual learning
GO_0060038	Biological process	cardiac muscle cell proliferation
GO_0060973	Biological process	cell migration involved in heart development
GO_0030154	Biological process	cell differentiation
GO_0048278	Biological process	vesicle docking
GO_0035050	Biological process	embryonic heart tube development
GO_0048662	Biological process	negative regulation of smooth muscle cell proliferation
GO_0070374	Biological process	positive regulation of ERK1 and ERK2 cascade
GO_2001135	Biological process	regulation of endocytic recycling
GO_0005886	Cellular component	plasma membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005739	Cellular component	mitochondrion
GO_0005829	Cellular component	cytosol
GO_0031253	Cellular component	cell projection membrane
GO_0005737	Cellular component	cytoplasm
GO_0016323	Cellular component	basolateral plasma membrane
GO_0005515	Molecular function	protein binding
GO_0003674	Molecular function	molecular_function

IV. Literature review

[source]

Gene name	NDRG4
Protein name	Protein NDRG4 (Brain development-related molecule 1) (N-myc downstream-regulated gene 4 protein) (Vascular smooth muscle cell-associated protein 8) (SMAP-8) NDRG family member 4 isoform 1 NDRG family member 4 NDRG family member 4 (cDNA, FLJ78988, highly similar to Protein NDRG4) NDRG family member 4 isoform 2 (NDRG family member 4, isoform CRA_a)
Synonyms	KIAA1180 hCG_15959 BDM1
Description	FUNCTION: Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner. .
Accessions	ENST00000566192.5 [Q9ULP0-2] ENST00000561724.5 ENST00000569026.1 H3BVF3 ENST00000570248.6 [Q9ULP0-1] ENST00000569404.5 ENST00000566618.5 ENST00000566656.5 ENST00000565088.5 H3BUK1 B7Z9X4 ENST00000563978.5 H3BNE7 H3BPT6 H3BQ86 H3BS80 H3BPH8 H3BU25 ENST00000564867.5 ENST00000565304.5 Q9ULP0 ENST00000568464.5 ENST00000564486.5 ENST00000565430.5 H3BR92 ENST00000562999.5 ENST00000568424.1 H3BN97 H3BSC3 ENST00000562731.5 H3BUH4 A0A0S2Z5R7 ENST00000568999.5 ENST00000569408.1 ENST00000394279.6 [Q9ULP0-3] H3BNB4 H3BNX9 ENST00000569923.5 ENST00000562930.5 H3BQ01 H3BM44 H3BRT9 H3BU08 H3BM83 ENST00000561738.5 A0A0S2Z5L7 ENST00000567454.5 ENST00000566041.5 ENST00000568640.5 [Q9ULP0-8] ENST00000564126.5 H3BMG5 ENST00000564207.5 ENST00000562764.5 H3BPY2 ENST00000565434.5 ENST00000566061.5 H3BQJ4 ENST00000567063.5 ENST00000356752.8 [Q9ULP0-7] ENST00000258187.9 [Q9ULP0-3] ENST00000563799.5 [Q9ULP0-5] H3BM40 H3BNK4 H3BN53 H3BNQ1 H3BST8 ENST00000394282.8 [Q9ULP0-6] H3BPQ3 ENST00000569539.5 H3BVB0 H3BMR6 ENST00000567667.5 ENST00000561779.5

NDRG4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review