LBX1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LBX1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LBX1 at tissue level.

III. Associated gene sets

GO_0009653Biological processanatomical structure morphogenesis
GO_0008285Biological processnegative regulation of cell population proliferation
GO_1905962Biological processglutamatergic neuron differentiation
GO_0048664Biological processneuron fate determination
GO_0008283Biological processcell population proliferation
GO_0120007Biological processnegative regulation of glutamatergic neuron differentiation
GO_0021522Biological processspinal cord motor neuron differentiation
GO_0007517Biological processmuscle organ development
GO_0001947Biological processheart looping
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameLBX1
Protein nameTranscription factor LBX1 (Ladybird homeobox protein homolog 1)
SynonymsLBX1H
DescriptionFUNCTION: Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord. .

AccessionsP52954
ENST00000370193.4