ARL13B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1905515Biological processnon-motile cilium assembly
GO_0060271Biological processcilium assembly
GO_0007224Biological processsmoothened signaling pathway
GO_0070986Biological processleft/right axis specification
GO_0001947Biological processheart looping
GO_0021532Biological processneural tube patterning
GO_0021830Biological processinterneuron migration from the subpallium to the cortex
GO_0009953Biological processdorsal/ventral pattern formation
GO_0097500Biological processreceptor localization to non-motile cilium
GO_0021943Biological processformation of radial glial scaffolds
GO_0031514Cellular componentmotile cilium
GO_0060170Cellular componentciliary membrane
GO_0005930Cellular componentaxoneme
GO_0097730Cellular componentnon-motile cilium
GO_0005929Cellular componentcilium
GO_0005829Cellular componentcytosol
GO_0005525Molecular functionGTP binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameARL13B
Protein nameADP ribosylation factor like GTPase 13B (cDNA FLJ60832, highly similar to Homo sapiens ADP-ribosylation factor-like 2-like 1 (ARL2L1), transcript variant 1, mRNA)
Alternative protein ARL13B
ADP ribosylation factor like GTPase 13B
ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1)
SynonymsARL2L1
DescriptionFUNCTION: Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidence is required to confirm these data. .

AccessionsA0A7P0Z4S0
F8W837
ENST00000679654.1
ENST00000460371.5
A0A7P0TAL8
ENST00000679872.1
ENST00000679666.1
A0A7P0T892
ENST00000679587.1
ENST00000335438.7
ENST00000679607.1
A0A7P0T9A8
ENST00000679657.1
ENST00000471138.5 [Q3SXY8-1]
ENST00000303097.11 [Q3SXY8-2]
A0A7P0T9C1
ENST00000680430.1
ENST00000486562.2
A0A7P0Z407
A0A7P0T8M9
ENST00000679739.1
A0A7P0T969
ENST00000679404.1
A0A7P0T8G9
F8WAY0
ENST00000394222.8 [Q3SXY8-1]
A0A7P0T933
ENST00000680414.1
L0R6C8
A0A7P0Z473
ENST00000679601.1
ENST00000681380.1
ENST00000681013.1
ENST00000535334.5 [Q3SXY8-3]
ENST00000681247.1
ENST00000681655.1
Q3SXY8
A0A7P0TAS1
A0A7P0Z4M2
B4DRI8