I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 29% ± 14% | |
| Mueller cell | 3 studies | 20% ± 5% | |
| ciliated cell | 3 studies | 29% ± 7% | |
| astrocyte | 3 studies | 39% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 29% ± 14% | |
| Mueller cell | 3 studies | 20% ± 5% | |
| ciliated cell | 3 studies | 29% ± 7% | |
| astrocyte | 3 studies | 39% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 26% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 773.28 | 653 / 653 | 98% | 10.90 | 594 / 605 |
| breast | 99% | 565.85 | 456 / 459 | 96% | 13.43 | 1076 / 1118 |
| kidney | 100% | 467.21 | 89 / 89 | 92% | 8.19 | 830 / 901 |
| pancreas | 99% | 197.77 | 324 / 328 | 92% | 4.58 | 163 / 178 |
| prostate | 100% | 639.20 | 245 / 245 | 89% | 5.89 | 445 / 502 |
| skin | 96% | 375.62 | 1738 / 1809 | 92% | 9.05 | 436 / 472 |
| lung | 99% | 349.20 | 573 / 578 | 86% | 6.30 | 994 / 1155 |
| uterus | 100% | 441.08 | 170 / 170 | 78% | 4.62 | 356 / 459 |
| bladder | 100% | 483.29 | 21 / 21 | 75% | 3.88 | 379 / 504 |
| adrenal gland | 100% | 1019.38 | 258 / 258 | 73% | 4.62 | 167 / 230 |
| liver | 96% | 204.61 | 216 / 226 | 72% | 4.00 | 294 / 406 |
| esophagus | 93% | 240.19 | 1341 / 1445 | 70% | 3.23 | 129 / 183 |
| ovary | 100% | 331.20 | 180 / 180 | 56% | 2.32 | 240 / 430 |
| brain | 87% | 241.36 | 2309 / 2642 | 67% | 2.83 | 475 / 705 |
| intestine | 100% | 356.28 | 963 / 966 | 55% | 1.94 | 289 / 527 |
| stomach | 98% | 206.66 | 353 / 359 | 47% | 1.63 | 134 / 286 |
| spleen | 100% | 329.52 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 99% | 282.81 | 1189 / 1204 | 0% | 0 | 0 / 0 |
| heart | 94% | 217.72 | 808 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 91% | 6.80 | 73 / 80 |
| blood vessel | 88% | 182.94 | 1177 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 4.00 | 34 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 41% | 2.03 | 12 / 29 |
| peripheral blood | 35% | 104.68 | 327 / 929 | 0% | 0 | 0 / 0 |
| muscle | 5% | 4.71 | 41 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0018009 | Biological process | N-terminal peptidyl-L-cysteine N-palmitoylation |
| GO_0007224 | Biological process | smoothened signaling pathway |
| GO_0018345 | Biological process | protein palmitoylation |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005525 | Molecular function | GTP binding |
| GO_0016409 | Molecular function | palmitoyltransferase activity |
| GO_0008374 | Molecular function | O-acyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HHAT |
| Protein name | HHAT protein Hedgehog acyltransferase (Protein-cysteine N-palmitoyltransferase HHAT) Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Melanoma antigen recognized by T-cells 2) (MART-2) (Skinny hedgehog protein 1) |
| Synonyms | MART2 SKI1 |
| Description | FUNCTION: Palmitoyl acyltransferase that catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling . It also catalyzes N-terminal palmitoylation of DHH . Promotes the transfer of palmitoyl-CoA from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane, where SHH palmitoylation occurs . It is an essential factor for proper embryonic development and testicular organogenesis . . |
| Accessions | ENST00000367009.2 Q5VTY9 ENST00000545154.5 [Q5VTY9-7] ENST00000631353 ENST00000628693.2 [Q5VTY9-7] ENST00000629360.3 [Q5VTY9-1] ENST00000626327.2 [Q5VTY9-5] ENST00000541565.5 [Q5VTY9-6] ENST00000426968.2 ENST00000625820.2 [Q5VTY9-1] ENST00000367010.5 [Q5VTY9-1] Q05BM0 ENST00000413764.6 [Q5VTY9-1] ENST00000629127 F5H2Y1 ENST00000628249 ENST00000627903.2 [Q5VTY9-1] ENST00000261458.8 [Q5VTY9-1] ENST00000545781.2 B1AK61 ENST00000537898.5 [Q5VTY9-5] ENST00000625523.2 [Q5VTY9-6] A0A075B6R5 |
