Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 13 studies | 33% ± 15% | |
endothelial cell | 11 studies | 28% ± 12% | |
oligodendrocyte precursor cell | 10 studies | 33% ± 16% | |
GABAergic neuron | 8 studies | 44% ± 23% | |
glutamatergic neuron | 8 studies | 45% ± 27% | |
oligodendrocyte | 8 studies | 28% ± 10% | |
astrocyte | 7 studies | 30% ± 13% | |
interneuron | 6 studies | 43% ± 25% | |
macrophage | 6 studies | 21% ± 5% | |
fibroblast | 6 studies | 22% ± 9% | |
neuron | 5 studies | 33% ± 15% | |
adipocyte | 5 studies | 21% ± 3% | |
granule cell | 4 studies | 23% ± 4% | |
microglial cell | 4 studies | 23% ± 4% | |
endothelial cell of lymphatic vessel | 4 studies | 26% ± 6% | |
GABAergic interneuron | 3 studies | 29% ± 2% | |
epithelial cell | 3 studies | 32% ± 9% | |
pericyte | 3 studies | 23% ± 8% | |
transit amplifying cell | 3 studies | 29% ± 19% | |
smooth muscle cell | 3 studies | 16% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 1685.59 | 245 / 245 | 100% | 13.52 | 500 / 502 |
brain | 100% | 1218.15 | 2631 / 2642 | 100% | 8.82 | 705 / 705 |
lung | 100% | 1482.23 | 578 / 578 | 99% | 7.33 | 1144 / 1155 |
breast | 100% | 1698.05 | 459 / 459 | 99% | 9.33 | 1107 / 1118 |
esophagus | 100% | 1136.81 | 1444 / 1445 | 98% | 6.80 | 180 / 183 |
pancreas | 99% | 831.29 | 326 / 328 | 98% | 5.40 | 175 / 178 |
thymus | 100% | 1405.99 | 653 / 653 | 97% | 6.00 | 588 / 605 |
uterus | 100% | 1967.53 | 170 / 170 | 97% | 6.70 | 443 / 459 |
ovary | 100% | 2001.91 | 180 / 180 | 96% | 5.01 | 412 / 430 |
bladder | 100% | 1337.00 | 21 / 21 | 95% | 5.48 | 480 / 504 |
kidney | 100% | 1041.72 | 89 / 89 | 95% | 9.21 | 857 / 901 |
intestine | 100% | 1357.82 | 966 / 966 | 95% | 5.76 | 501 / 527 |
stomach | 100% | 1008.85 | 359 / 359 | 94% | 5.67 | 268 / 286 |
adrenal gland | 100% | 902.63 | 258 / 258 | 93% | 7.24 | 215 / 230 |
skin | 100% | 1482.13 | 1809 / 1809 | 92% | 7.79 | 434 / 472 |
liver | 100% | 559.15 | 226 / 226 | 78% | 3.48 | 317 / 406 |
adipose | 100% | 1527.46 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 4.77 | 29 / 29 |
muscle | 100% | 1439.59 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1241.61 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.40 | 1 / 1 |
blood vessel | 100% | 1324.90 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 983.61 | 846 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 5.88 | 44 / 45 |
eye | 0% | 0 | 0 / 0 | 83% | 5.14 | 66 / 80 |
peripheral blood | 53% | 479.67 | 489 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008589 | Biological process | regulation of smoothened signaling pathway |
GO_0060271 | Biological process | cilium assembly |
GO_0061512 | Biological process | protein localization to cilium |
GO_0007224 | Biological process | smoothened signaling pathway |
GO_0060020 | Biological process | Bergmann glial cell differentiation |
GO_0021702 | Biological process | cerebellar Purkinje cell differentiation |
GO_0090263 | Biological process | positive regulation of canonical Wnt signaling pathway |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0035721 | Biological process | intraciliary retrograde transport |
GO_0021798 | Biological process | forebrain dorsal/ventral pattern formation |
GO_1903999 | Biological process | negative regulation of eating behavior |
GO_0097499 | Biological process | protein localization to non-motile cilium |
GO_0021591 | Biological process | ventricular system development |
GO_1905799 | Biological process | regulation of intraciliary retrograde transport |
GO_0005856 | Cellular component | cytoskeleton |
GO_0097542 | Cellular component | ciliary tip |
GO_0030991 | Cellular component | intraciliary transport particle A |
GO_0005929 | Cellular component | cilium |
GO_0005737 | Cellular component | cytoplasm |
GO_0003682 | Molecular function | chromatin binding |
GO_0005515 | Molecular function | protein binding |
Gene name | TTC21B |
Protein name | Tetratricopeptide repeat domain 21B Tetratricopeptide repeat protein 21B (TPR repeat protein 21B) (Intraflagellar transport 139 homolog) |
Synonyms | Nbla10696 IFT139 KIAA1992 |
Description | FUNCTION: Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Essential for retrograde trafficking of IFT-1, IFT-B and GPCRs . Negatively modulates the SHH signal transduction (By similarity). . |
Accessions | ENST00000680448.1 A0A7P0TAK1 A0A7P0T962 A0A7P0T9H7 ENST00000680947.1 A0A7P0TBF6 ENST00000679931.1 ENST00000681024.1 ENST00000681819.1 A0A7P0TB56 ENST00000679356.1 ENST00000681083.1 ENST00000679799.1 A0A7P0TBE5 A0A7P0Z487 A0A7P0TB61 ENST00000652557.1 A0A7P0TA66 A0A7P0TAJ8 H9KV93 ENST00000680888.1 [Q7Z4L5-1] Q7Z4L5 ENST00000679840.1 A0A7P0TAA5 A0A494C0N4 ENST00000681502.1 ENST00000392695.6 ENST00000681483.1 ENST00000681606.1 ENST00000681952.1 [Q7Z4L5-1] A0A7P0Z4B3 ENST00000679967.1 ENST00000680690.1 A0A7P0T8P4 A0A7P0T968 ENST00000680327.1 ENST00000243344.8 [Q7Z4L5-1] ENST00000679676.1 |