I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 9 studies | 25% ± 8% | |
| GABAergic neuron | 3 studies | 26% ± 6% | |
| glutamatergic neuron | 3 studies | 28% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 9 studies | 25% ± 8% | |
| GABAergic neuron | 3 studies | 26% ± 6% | |
| glutamatergic neuron | 3 studies | 28% ± 7% |
Insufficient scRNA-seq data for expression of TCTN2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 930.35 | 245 / 245 | 99% | 16.27 | 497 / 502 |
| breast | 100% | 863.13 | 459 / 459 | 97% | 14.69 | 1086 / 1118 |
| ovary | 100% | 1324.39 | 180 / 180 | 97% | 15.66 | 417 / 430 |
| lung | 100% | 690.35 | 576 / 578 | 97% | 10.36 | 1117 / 1155 |
| kidney | 100% | 873.81 | 89 / 89 | 96% | 19.81 | 865 / 901 |
| skin | 100% | 835.19 | 1807 / 1809 | 96% | 11.87 | 452 / 472 |
| uterus | 100% | 1233.20 | 170 / 170 | 96% | 10.57 | 439 / 459 |
| pancreas | 97% | 381.68 | 319 / 328 | 98% | 9.95 | 175 / 178 |
| bladder | 100% | 595.90 | 21 / 21 | 95% | 8.80 | 479 / 504 |
| thymus | 100% | 1289.36 | 653 / 653 | 95% | 11.11 | 574 / 605 |
| brain | 96% | 576.90 | 2524 / 2642 | 98% | 10.45 | 692 / 705 |
| intestine | 100% | 556.78 | 962 / 966 | 94% | 7.07 | 494 / 527 |
| stomach | 99% | 471.44 | 356 / 359 | 94% | 7.42 | 269 / 286 |
| esophagus | 99% | 480.73 | 1432 / 1445 | 93% | 9.35 | 170 / 183 |
| adrenal gland | 97% | 461.40 | 249 / 258 | 89% | 9.55 | 205 / 230 |
| spleen | 100% | 405.80 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.15 | 1 / 1 |
| blood vessel | 100% | 555.58 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 604.96 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 9.88 | 43 / 45 |
| eye | 0% | 0 | 0 / 0 | 90% | 6.98 | 72 / 80 |
| heart | 89% | 288.63 | 766 / 861 | 0% | 0 | 0 / 0 |
| muscle | 41% | 78.31 | 328 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 38% | 1.55 | 11 / 29 |
| liver | 13% | 22.69 | 29 / 226 | 23% | 2.52 | 95 / 406 |
| peripheral blood | 23% | 102.77 | 213 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0060271 | Biological process | cilium assembly |
| GO_0007224 | Biological process | smoothened signaling pathway |
| GO_1904491 | Biological process | protein localization to ciliary transition zone |
| GO_0060170 | Cellular component | ciliary membrane |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0036038 | Cellular component | MKS complex |
| GO_0005737 | Cellular component | cytoplasm |
| Gene name | TCTN2 |
| Protein name | HCG2033819, isoform CRA_b (Tectonic family member 2) Tectonic family member 2 Tectonic-2 |
| Synonyms | TECT2 C12orf38 hCG_2033819 |
| Description | FUNCTION: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity). . |
| Accessions | ENST00000541523.1 A0A7P0TAX5 ENST00000679504.1 A0A7P0T886 A0A7P0T8X4 F5H6G0 ENST00000303372.7 [Q96GX1-1] ENST00000680574.1 ENST00000680500.1 Q96GX1 ENST00000426174.6 [Q96GX1-2] |
