Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 21 studies | 25% ± 9% | |
| pericyte | 19 studies | 25% ± 7% | |
| ciliated cell | 17 studies | 55% ± 15% | |
| fibroblast | 17 studies | 23% ± 11% | |
| astrocyte | 13 studies | 30% ± 11% | |
| endothelial cell | 12 studies | 25% ± 9% | |
| connective tissue cell | 11 studies | 26% ± 9% | |
| epithelial cell | 10 studies | 32% ± 18% | |
| myofibroblast cell | 9 studies | 23% ± 5% | |
| retinal rod cell | 9 studies | 47% ± 19% | |
| neuron | 8 studies | 33% ± 14% | |
| epithelial cell of proximal tubule | 7 studies | 23% ± 6% | |
| retinal cone cell | 7 studies | 54% ± 25% | |
| oligodendrocyte precursor cell | 7 studies | 28% ± 7% | |
| glutamatergic neuron | 6 studies | 39% ± 19% | |
| basal cell | 6 studies | 33% ± 11% | |
| GABAergic neuron | 6 studies | 33% ± 15% | |
| interneuron | 6 studies | 29% ± 16% | |
| kidney loop of Henle epithelial cell | 5 studies | 24% ± 5% | |
| retinal ganglion cell | 5 studies | 52% ± 26% | |
| oligodendrocyte | 5 studies | 20% ± 3% | |
| deuterosomal cell | 4 studies | 20% ± 0% | |
| pancreatic A cell | 4 studies | 55% ± 16% | |
| retinal bipolar neuron | 4 studies | 46% ± 23% | |
| OFF-bipolar cell | 4 studies | 39% ± 14% | |
| ON-bipolar cell | 4 studies | 41% ± 12% | |
| amacrine cell | 4 studies | 41% ± 12% | |
| retina horizontal cell | 4 studies | 44% ± 13% | |
| Mueller cell | 4 studies | 39% ± 9% | |
| goblet cell | 4 studies | 28% ± 11% | |
| ionocyte | 3 studies | 31% ± 4% | |
| pancreatic D cell | 3 studies | 49% ± 21% | |
| type B pancreatic cell | 3 studies | 54% ± 8% | |
| conventional dendritic cell | 3 studies | 22% ± 3% | |
| progenitor cell | 3 studies | 19% ± 2% | |
| kidney distal convoluted tubule epithelial cell | 3 studies | 28% ± 8% | |
| mesothelial cell | 3 studies | 27% ± 16% | |
| neural crest cell | 3 studies | 25% ± 1% | |
| retinal pigment epithelial cell | 3 studies | 33% ± 14% | |
| rod bipolar cell | 3 studies | 59% ± 13% | |
| erythroblast | 3 studies | 17% ± 1% | |
| luminal hormone-sensing cell of mammary gland | 3 studies | 18% ± 2% | |
| macrophage | 3 studies | 18% ± 3% | |
| dendritic cell | 3 studies | 23% ± 5% | |
| enteroendocrine cell | 3 studies | 31% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 4234.81 | 2642 / 2642 | 100% | 70.32 | 705 / 705 |
| thymus | 100% | 2192.87 | 653 / 653 | 100% | 42.96 | 604 / 605 |
| ovary | 100% | 2994.28 | 180 / 180 | 100% | 28.53 | 429 / 430 |
| breast | 100% | 1593.86 | 459 / 459 | 99% | 41.83 | 1110 / 1118 |
| kidney | 100% | 2259.44 | 89 / 89 | 99% | 28.38 | 893 / 901 |
| prostate | 100% | 1724.29 | 244 / 245 | 99% | 28.56 | 499 / 502 |
| lung | 99% | 1609.93 | 575 / 578 | 99% | 22.05 | 1148 / 1155 |
| uterus | 100% | 2383.56 | 170 / 170 | 99% | 29.35 | 453 / 459 |
| adrenal gland | 100% | 1479.66 | 258 / 258 | 98% | 41.13 | 226 / 230 |
| bladder | 100% | 1821.29 | 21 / 21 | 98% | 21.15 | 494 / 504 |
| stomach | 99% | 1338.67 | 357 / 359 | 98% | 15.54 | 281 / 286 |
| intestine | 98% | 1614.00 | 948 / 966 | 98% | 16.89 | 517 / 527 |
| skin | 100% | 1576.79 | 1806 / 1809 | 94% | 14.71 | 443 / 472 |
| esophagus | 97% | 1574.42 | 1402 / 1445 | 94% | 13.68 | 172 / 183 |
| pancreas | 80% | 557.64 | 264 / 328 | 99% | 24.38 | 176 / 178 |
| liver | 46% | 267.80 | 105 / 226 | 85% | 11.13 | 346 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 26.52 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.01 | 1 / 1 |
| blood vessel | 100% | 2050.64 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 1395.31 | 1201 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 99% | 836.71 | 238 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 16.70 | 28 / 29 |
| heart | 95% | 1587.18 | 819 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 85% | 10.69 | 68 / 80 |
| muscle | 78% | 538.24 | 628 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 53% | 633.24 | 492 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0060271 | Biological process | cilium assembly |
| GO_0061512 | Biological process | protein localization to cilium |
| GO_0007224 | Biological process | smoothened signaling pathway |
| GO_0006892 | Biological process | post-Golgi vesicle-mediated transport |
| GO_0001822 | Biological process | kidney development |
| GO_0000281 | Biological process | mitotic cytokinesis |
| GO_0042461 | Biological process | photoreceptor cell development |
| GO_0007264 | Biological process | small GTPase-mediated signal transduction |
| GO_0006893 | Biological process | Golgi to plasma membrane transport |
| GO_0015031 | Biological process | protein transport |
| GO_0042073 | Biological process | intraciliary transport |
| GO_1903441 | Biological process | protein localization to ciliary membrane |
| GO_0005876 | Cellular component | spindle microtubule |
| GO_0030496 | Cellular component | midbody |
| GO_0032391 | Cellular component | photoreceptor connecting cilium |
| GO_0005813 | Cellular component | centrosome |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005929 | Cellular component | cilium |
| GO_0015630 | Cellular component | microtubule cytoskeleton |
| GO_0005881 | Cellular component | cytoplasmic microtubule |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0019003 | Molecular function | GDP binding |
| GO_0000287 | Molecular function | magnesium ion binding |
| GO_0005525 | Molecular function | GTP binding |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | ARL3 |
| Protein name | ADP-ribosylation factor-like protein 3 |
| Synonyms | ARFL3 |
| Description | FUNCTION: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP) . Required for normal cytokinesis and cilia signaling . Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins to the cilium, including myristoylated NPHP3 and prenylated INPP5E . Targets NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium . Required for PKD1:PKD2 complex targeting from the trans-Golgi network to the cilium (By similarity). . |
| Accessions | ENST00000260746.6 P36405 |