G2/M transition of mitotic cell cycle

I. Literature review

[source]
NameG2/M transition of mitotic cell cycle
IDGO_0000086
collection_id

Biological process

Exact synonym

mitotic G2/M transition

Description

The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.

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Genes