CCDC57 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0000086Biological processG2/M transition of mitotic cell cycle
GO_0045931Biological processpositive regulation of mitotic cell cycle
GO_0007020Biological processmicrotubule nucleation
GO_0007099Biological processcentriole replication
GO_0005814Cellular componentcentriole
GO_0005813Cellular componentcentrosome
GO_0005876Cellular componentspindle microtubule
GO_0034451Cellular componentcentriolar satellite
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCCDC57
Protein nameCoiled-coil domain-containing protein 57
Coiled-coil domain containing 57
Synonyms
DescriptionFUNCTION: Pleiotropic regulator of centriole duplication, mitosis, and ciliogenesis. Critical interface between centrosome and microtubule-mediated cellular processes. Centriole duplication protein required for recruitment of CEP63, CEP152, and PLK4 to the centrosome. Independent of its centrosomal targeting, localizes to and interacts with microtubules and regulates microtubule nucleation, stability, and mitotic progression. .

AccessionsH7BYI8
ENST00000419322.6
J3KRQ8
K7N7D6
A0A590UJT6
Q2TAC2
ENST00000583593.2
J3QQX7
A0A8Q3SHK3
ENST00000389641.9 [Q2TAC2-1]
J3KSU5
ENST00000581625.2
ENST00000665763.1
ENST00000392343.3 [Q2TAC2-2]
ENST00000583053.1
ENST00000694881.1
ENST00000694882.1
ENST00000392345.6