Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 8 studies | 22% ± 7% | |
| epithelial cell | 7 studies | 32% ± 15% | |
| neuron | 5 studies | 30% ± 11% | |
| fibroblast | 4 studies | 19% ± 5% | |
| regulatory T cell | 4 studies | 17% ± 1% | |
| macrophage | 4 studies | 16% ± 1% | |
| GABAergic neuron | 4 studies | 40% ± 16% | |
| astrocyte | 4 studies | 26% ± 4% | |
| glutamatergic neuron | 4 studies | 49% ± 18% | |
| interneuron | 4 studies | 33% ± 20% | |
| oligodendrocyte | 4 studies | 24% ± 3% | |
| hematopoietic precursor cell | 3 studies | 21% ± 6% | |
| retinal ganglion cell | 3 studies | 45% ± 25% | |
| ciliated cell | 3 studies | 25% ± 3% | |
| oligodendrocyte precursor cell | 3 studies | 28% ± 5% | |
| dendritic cell | 3 studies | 25% ± 5% | |
| abnormal cell | 3 studies | 18% ± 1% | |
| enteroendocrine cell | 3 studies | 25% ± 10% | |
| basal cell | 3 studies | 30% ± 5% | |
| goblet cell | 3 studies | 22% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 1623.66 | 258 / 258 | 100% | 58.33 | 230 / 230 |
| esophagus | 100% | 1133.00 | 1445 / 1445 | 100% | 28.72 | 183 / 183 |
| pancreas | 100% | 1622.31 | 328 / 328 | 100% | 37.56 | 178 / 178 |
| prostate | 100% | 1425.49 | 245 / 245 | 100% | 46.35 | 502 / 502 |
| skin | 100% | 1831.15 | 1809 / 1809 | 100% | 46.83 | 472 / 472 |
| stomach | 100% | 1110.75 | 359 / 359 | 100% | 36.96 | 286 / 286 |
| thymus | 100% | 1305.13 | 653 / 653 | 100% | 60.92 | 605 / 605 |
| uterus | 100% | 1469.66 | 170 / 170 | 100% | 45.99 | 459 / 459 |
| brain | 100% | 2158.97 | 2641 / 2642 | 100% | 46.72 | 705 / 705 |
| kidney | 100% | 1562.87 | 89 / 89 | 100% | 43.73 | 900 / 901 |
| breast | 100% | 1320.44 | 459 / 459 | 100% | 64.83 | 1116 / 1118 |
| ovary | 100% | 1678.68 | 180 / 180 | 100% | 41.32 | 429 / 430 |
| intestine | 100% | 1337.62 | 966 / 966 | 100% | 43.15 | 525 / 527 |
| bladder | 100% | 1184.95 | 21 / 21 | 100% | 47.10 | 502 / 504 |
| lung | 99% | 1047.25 | 574 / 578 | 100% | 36.32 | 1155 / 1155 |
| liver | 85% | 352.38 | 191 / 226 | 92% | 18.44 | 375 / 406 |
| adipose | 100% | 1170.95 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 57.06 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 61.34 | 29 / 29 |
| muscle | 100% | 1833.74 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1094.02 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 40.32 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 20.26 | 1 / 1 |
| blood vessel | 100% | 1178.45 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 1290.03 | 845 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 93% | 810.50 | 860 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006479 | Biological process | protein methylation |
| GO_0000086 | Biological process | G2/M transition of mitotic cell cycle |
| GO_0031333 | Biological process | negative regulation of protein-containing complex assembly |
| GO_0042981 | Biological process | regulation of apoptotic process |
| GO_0010906 | Biological process | regulation of glucose metabolic process |
| GO_0036211 | Biological process | protein modification process |
| GO_0006481 | Biological process | C-terminal protein methylation |
| GO_0090266 | Biological process | regulation of mitotic cell cycle spindle assembly checkpoint |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0003880 | Molecular function | protein C-terminal carboxyl O-methyltransferase activity |
| GO_0018423 | Molecular function | protein C-terminal leucine carboxyl O-methyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008757 | Molecular function | S-adenosylmethionine-dependent methyltransferase activity |
| Gene name | LCMT1 |
| Protein name | [phosphatase 2A protein]-leucine-carboxy methyltransferase (EC 2.1.1.233) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1) Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) (Protein-leucine O-methyltransferase) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1) Leucine carboxyl methyltransferase 1 |
| Synonyms | LCMT CGI-68 |
| Description | FUNCTION: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. . FUNCTION: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. . FUNCTION: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. . |
| Accessions | ENST00000570981.1 I3L4A2 ENST00000576625.5 ENST00000572761.1 I3L2Q8 I3L537 ENST00000380962.9 ENST00000399069.8 [Q9UIC8-1] ENST00000575396.1 ENST00000564011.5 I3L2E3 H7BYF0 ENST00000380966.8 [Q9UIC8-3] H3BUP7 Q9UIC8 |