LCMT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006479Biological processprotein methylation
GO_0000086Biological processG2/M transition of mitotic cell cycle
GO_0031333Biological processnegative regulation of protein-containing complex assembly
GO_0042981Biological processregulation of apoptotic process
GO_0010906Biological processregulation of glucose metabolic process
GO_0036211Biological processprotein modification process
GO_0006481Biological processC-terminal protein methylation
GO_0090266Biological processregulation of mitotic cell cycle spindle assembly checkpoint
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0003880Molecular functionprotein C-terminal carboxyl O-methyltransferase activity
GO_0018423Molecular functionprotein C-terminal leucine carboxyl O-methyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0008757Molecular functionS-adenosylmethionine-dependent methyltransferase activity

IV. Literature review

[source]
Gene nameLCMT1
Protein name[phosphatase 2A protein]-leucine-carboxy methyltransferase (EC 2.1.1.233) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1)
Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) (Protein-leucine O-methyltransferase) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1)
Leucine carboxyl methyltransferase 1
SynonymsLCMT
CGI-68
DescriptionFUNCTION: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. .

FUNCTION: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. .

FUNCTION: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. .

AccessionsENST00000570981.1
I3L4A2
ENST00000576625.5
ENST00000572761.1
I3L2Q8
I3L537
ENST00000380962.9
ENST00000399069.8 [Q9UIC8-1]
ENST00000575396.1
ENST00000564011.5
I3L2E3
H7BYF0
ENST00000380966.8 [Q9UIC8-3]
H3BUP7
Q9UIC8