Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 25 studies | 52% ± 19% | |
astrocyte | 18 studies | 68% ± 25% | |
oligodendrocyte | 16 studies | 62% ± 18% | |
fibroblast | 15 studies | 54% ± 16% | |
smooth muscle cell | 13 studies | 45% ± 17% | |
oligodendrocyte precursor cell | 13 studies | 52% ± 13% | |
pericyte | 11 studies | 38% ± 16% | |
GABAergic neuron | 9 studies | 33% ± 12% | |
endothelial cell of lymphatic vessel | 9 studies | 62% ± 21% | |
mesothelial cell | 8 studies | 46% ± 16% | |
adipocyte | 7 studies | 39% ± 10% | |
cardiac muscle cell | 6 studies | 56% ± 22% | |
vein endothelial cell | 6 studies | 47% ± 24% | |
epithelial cell | 5 studies | 35% ± 17% | |
microglial cell | 5 studies | 47% ± 25% | |
capillary endothelial cell | 5 studies | 32% ± 14% | |
granule cell | 4 studies | 28% ± 12% | |
interneuron | 4 studies | 30% ± 13% | |
neuron | 4 studies | 36% ± 12% | |
endothelial cell of artery | 4 studies | 44% ± 20% | |
Mueller cell | 4 studies | 37% ± 9% | |
retina horizontal cell | 4 studies | 84% ± 9% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 57% ± 12% | |
GABAergic interneuron | 3 studies | 29% ± 9% | |
glial cell | 3 studies | 47% ± 14% | |
progenitor cell | 3 studies | 58% ± 12% | |
endocardial cell | 3 studies | 45% ± 21% | |
GABAergic amacrine cell | 3 studies | 30% ± 8% | |
glycinergic amacrine cell | 3 studies | 30% ± 2% | |
retinal ganglion cell | 3 studies | 51% ± 15% | |
endothelial cell of vascular tree | 3 studies | 59% ± 5% | |
ependymal cell | 3 studies | 65% ± 8% | |
myofibroblast cell | 3 studies | 53% ± 25% | |
type I pneumocyte | 3 studies | 24% ± 5% | |
basal cell | 3 studies | 29% ± 5% | |
glutamatergic neuron | 3 studies | 33% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 2743.91 | 245 / 245 | 97% | 12.82 | 489 / 502 |
breast | 100% | 2870.91 | 459 / 459 | 92% | 26.25 | 1024 / 1118 |
brain | 89% | 1338.01 | 2349 / 2642 | 100% | 30.45 | 703 / 705 |
ovary | 100% | 5066.05 | 180 / 180 | 76% | 11.18 | 327 / 430 |
thymus | 100% | 1747.78 | 650 / 653 | 75% | 7.34 | 454 / 605 |
adrenal gland | 100% | 4182.26 | 258 / 258 | 72% | 19.90 | 166 / 230 |
skin | 89% | 1269.98 | 1616 / 1809 | 77% | 23.40 | 365 / 472 |
lung | 100% | 1882.97 | 577 / 578 | 62% | 7.48 | 713 / 1155 |
esophagus | 94% | 2109.64 | 1364 / 1445 | 62% | 6.98 | 113 / 183 |
kidney | 76% | 661.53 | 68 / 89 | 79% | 11.62 | 708 / 901 |
uterus | 100% | 4756.76 | 170 / 170 | 36% | 13.37 | 165 / 459 |
stomach | 80% | 1722.91 | 288 / 359 | 55% | 6.09 | 156 / 286 |
bladder | 100% | 3324.67 | 21 / 21 | 34% | 2.88 | 169 / 504 |
intestine | 96% | 2424.50 | 929 / 966 | 36% | 3.28 | 191 / 527 |
adipose | 100% | 3270.71 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3588.61 | 1335 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 2011.28 | 857 / 861 | 0% | 0 | 0 / 0 |
spleen | 96% | 975.32 | 232 / 241 | 0% | 0 | 0 / 0 |
pancreas | 8% | 45.17 | 26 / 328 | 83% | 10.00 | 147 / 178 |
eye | 0% | 0 | 0 / 0 | 54% | 5.53 | 43 / 80 |
muscle | 45% | 297.13 | 361 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 38% | 5.09 | 17 / 45 |
liver | 3% | 20.37 | 7 / 226 | 31% | 2.71 | 126 / 406 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.50 | 3 / 29 |
peripheral blood | 0% | 0.71 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0000086 | Biological process | G2/M transition of mitotic cell cycle |
GO_0016567 | Biological process | protein ubiquitination |
GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
GO_0031146 | Biological process | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
GO_0051301 | Biological process | cell division |
GO_0000278 | Biological process | mitotic cell cycle |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0019005 | Cellular component | SCF ubiquitin ligase complex |
GO_0000151 | Cellular component | ubiquitin ligase complex |
GO_0005813 | Cellular component | centrosome |
GO_0005829 | Cellular component | cytosol |
GO_0005515 | Molecular function | protein binding |
Gene name | FBXL7 |
Protein name | Alternative protein FBXL7 F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7) F-box and leucine rich repeat protein 7 |
Synonyms | FBL7 KIAA0840 FBL6 |
Description | FUNCTION: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex . During mitosis, it mediates the ubiquitination and subsequent proteasomal degradation of AURKA, causing mitotic arrest (By similarity). It also regulates mitochondrial function by mediating the ubiquitination and proteasomal degradation of the apoptosis inhibitor BIRC5 . . |
Accessions | J3KNM9 ENST00000510662.1 [Q9UJT9-2] L8EAM2 Q9UJT9 ENST00000504595.2 [Q9UJT9-1] ENST00000329673.8 |