FOXM1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FOXM1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FOXM1 at tissue level.

III. Associated gene sets

GO_2000377Biological processregulation of reactive oxygen species metabolic process
GO_0006281Biological processDNA repair
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0046578Biological processregulation of Ras protein signal transduction
GO_0006978Biological processDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0032873Biological processnegative regulation of stress-activated MAPK cascade
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0000086Biological processG2/M transition of mitotic cell cycle
GO_0008284Biological processpositive regulation of cell population proliferation
GO_2000781Biological processpositive regulation of double-strand break repair
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0042127Biological processregulation of cell population proliferation
GO_0051726Biological processregulation of cell cycle
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0019901Molecular functionprotein kinase binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFOXM1
Protein nameFOXM1A (Forkhead box M1, isoform CRA_b)
A novel forkhead box M1 isoform FOXM1D (Forkhead box M1-D)
FOXM1B (Forkhead box M1, isoform CRA_c)
Forkhead box M1
FOXM1C (Forkhead box M1) (PIG29)
Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells)
SynonymsHFH11
WIN
hCG_1731745
MPP2
FKHL16
DescriptionFUNCTION: Transcription factor regulating the expression of cell cycle genes essential for DNA replication and mitosis . Plays a role in the control of cell proliferation . Also plays a role in DNA break repair, participating in the DNA damage checkpoint response . Promotes transcription of PHB2 . .

AccessionsENST00000359843.8 [Q08050-1]
Q53Y49
H0YG99
ENST00000538564.5
ENST00000342628.6 [Q08050-3]
A0A2P9DTZ1
ENST00000535350.1
Q08050
ENST00000361953.7 [Q08050-2]
A0A2P9DTZ0
ENST00000627656.2
H0YGS4
A0A0D9SFF0
A0A2P9DTZ8