CDC25B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010971Biological processpositive regulation of G2/M transition of mitotic cell cycle
GO_0000278Biological processmitotic cell cycle
GO_0051301Biological processcell division
GO_0001556Biological processoocyte maturation
GO_0045931Biological processpositive regulation of mitotic cell cycle
GO_0007144Biological processfemale meiosis I
GO_0000086Biological processG2/M transition of mitotic cell cycle
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0006468Biological processprotein phosphorylation
GO_0032467Biological processpositive regulation of cytokinesis
GO_0110032Biological processpositive regulation of G2/MI transition of meiotic cell cycle
GO_0000922Cellular componentspindle pole
GO_0005813Cellular componentcentrosome
GO_0005634Cellular componentnucleus
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0004721Molecular functionphosphoprotein phosphatase activity
GO_0019901Molecular functionprotein kinase binding
GO_0005515Molecular functionprotein binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameCDC25B
Protein nameM-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)
M-phase inducer phosphatase (EC 3.1.3.48)
Alternative protein CDC25B
Cdc25B phosphatase
SynonymshCG_39252
CDC25HU2
DescriptionFUNCTION: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression . Directly dephosphorylates CDK1 and stimulates its kinase activity . Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner . The three isoforms seem to have a different level of activity . .

FUNCTION: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. .

FUNCTION: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. .

FUNCTION: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. .

FUNCTION: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. .

AccessionsO43550
Q7LDQ7
E1YMX4
ENST00000379598.9
ENST00000245960.10 [P30305-1]
ENST00000344256.10
ENST00000340833.4 [P30305-3]
B4DIG0
ENST00000439880.6 [P30305-2]
G8JLH2
B3KS38
L8E819
P30305