Insufficient scRNA-seq data for expression of CDC25A at single-cell level.
Insufficient scRNA-seq data for expression of CDC25A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 99% | 195.28 | 178 / 180 | 88% | 8.28 | 378 / 430 |
skin | 91% | 261.04 | 1649 / 1809 | 93% | 11.72 | 440 / 472 |
stomach | 92% | 121.37 | 329 / 359 | 93% | 13.85 | 265 / 286 |
uterus | 79% | 47.40 | 134 / 170 | 98% | 15.41 | 449 / 459 |
bladder | 81% | 56.10 | 17 / 21 | 92% | 12.67 | 462 / 504 |
intestine | 76% | 160.87 | 730 / 966 | 94% | 15.98 | 493 / 527 |
esophagus | 77% | 157.58 | 1108 / 1445 | 90% | 9.40 | 165 / 183 |
prostate | 99% | 112.85 | 243 / 245 | 65% | 3.42 | 324 / 502 |
brain | 93% | 84.70 | 2461 / 2642 | 65% | 5.81 | 461 / 705 |
breast | 82% | 53.30 | 376 / 459 | 74% | 7.23 | 823 / 1118 |
adrenal gland | 98% | 118.37 | 254 / 258 | 47% | 3.59 | 107 / 230 |
lung | 66% | 59.24 | 384 / 578 | 73% | 7.23 | 843 / 1155 |
thymus | 100% | 145.11 | 652 / 653 | 39% | 3.42 | 234 / 605 |
pancreas | 84% | 56.35 | 274 / 328 | 41% | 2.92 | 73 / 178 |
kidney | 99% | 94.91 | 88 / 89 | 8% | 0.43 | 68 / 901 |
lymph node | 0% | 0 | 0 / 0 | 100% | 20.33 | 29 / 29 |
spleen | 100% | 350.69 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.68 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.39 | 1 / 1 |
liver | 56% | 49.96 | 126 / 226 | 34% | 2.35 | 138 / 406 |
adipose | 78% | 48.18 | 937 / 1204 | 0% | 0 | 0 / 0 |
heart | 74% | 50.49 | 637 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 65% | 492.67 | 605 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 63% | 34.57 | 841 / 1335 | 0% | 0 | 0 / 0 |
muscle | 60% | 38.85 | 483 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 16% | 0.62 | 13 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010971 | Biological process | positive regulation of G2/M transition of mitotic cell cycle |
GO_0008283 | Biological process | cell population proliferation |
GO_0034644 | Biological process | cellular response to UV |
GO_0009314 | Biological process | response to radiation |
GO_0000079 | Biological process | regulation of cyclin-dependent protein serine/threonine kinase activity |
GO_0051301 | Biological process | cell division |
GO_0045740 | Biological process | positive regulation of DNA replication |
GO_0000086 | Biological process | G2/M transition of mitotic cell cycle |
GO_0000082 | Biological process | G1/S transition of mitotic cell cycle |
GO_0110032 | Biological process | positive regulation of G2/MI transition of meiotic cell cycle |
GO_0005634 | Cellular component | nucleus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0004721 | Molecular function | phosphoprotein phosphatase activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0051087 | Molecular function | protein-folding chaperone binding |
GO_0005515 | Molecular function | protein binding |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | CDC25A |
Protein name | M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A) M-phase inducer phosphatase (EC 3.1.3.48) Cell division cycle 25A |
Synonyms | |
Description | FUNCTION: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression . Directly dephosphorylates CDK1 and stimulates its kinase activity . Also dephosphorylates CDK2 in complex with cyclin-E, in vitro . . FUNCTION: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. . |
Accessions | ENST00000302506.8 [P30304-1] ENST00000351231.7 [P30304-2] C9JH94 D8KXX0 ENST00000437972.1 C9JFR5 P30304 ENST00000443342.5 |