PPME1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000086Biological processG2/M transition of mitotic cell cycle
GO_0006482Biological processprotein demethylation
GO_0005654Cellular componentnucleoplasm
GO_0004864Molecular functionprotein phosphatase inhibitor activity
GO_0051722Molecular functionprotein C-terminal methylesterase activity
GO_0045296Molecular functioncadherin binding
GO_0051721Molecular functionprotein phosphatase 2A binding
GO_0019888Molecular functionprotein phosphatase regulator activity
GO_0019901Molecular functionprotein kinase binding
GO_0051723Molecular functionprotein methylesterase activity
GO_0106222Molecular functionlncRNA binding
GO_0005515Molecular functionprotein binding
GO_0019903Molecular functionprotein phosphatase binding

IV. Literature review

[source]
Gene namePPME1
Protein nameProtein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89)
SynonymsPP2593
PRO0750
PME1
DescriptionFUNCTION: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. .

AccessionsQ9Y570
ENST00000398427.6 [Q9Y570-4]
ENST00000328257.13 [Q9Y570-1]