Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 10 studies | 38% ± 25% | |
endothelial cell | 7 studies | 29% ± 8% | |
GABAergic neuron | 7 studies | 37% ± 20% | |
ciliated cell | 6 studies | 26% ± 8% | |
oligodendrocyte | 6 studies | 23% ± 7% | |
astrocyte | 5 studies | 31% ± 10% | |
neuron | 4 studies | 30% ± 5% | |
microglial cell | 4 studies | 21% ± 2% | |
epithelial cell | 4 studies | 33% ± 6% | |
oligodendrocyte precursor cell | 4 studies | 25% ± 8% | |
erythrocyte | 4 studies | 54% ± 14% | |
interneuron | 4 studies | 45% ± 22% | |
abnormal cell | 3 studies | 22% ± 5% | |
basal cell | 3 studies | 26% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 3391.59 | 258 / 258 | 100% | 28.50 | 230 / 230 |
esophagus | 100% | 2670.15 | 1445 / 1445 | 100% | 35.10 | 183 / 183 |
intestine | 100% | 2086.42 | 966 / 966 | 100% | 24.27 | 527 / 527 |
ovary | 100% | 2448.29 | 180 / 180 | 100% | 28.16 | 430 / 430 |
prostate | 100% | 3182.66 | 245 / 245 | 100% | 31.13 | 502 / 502 |
skin | 100% | 4222.94 | 1809 / 1809 | 100% | 28.31 | 472 / 472 |
stomach | 100% | 1644.74 | 359 / 359 | 100% | 23.78 | 286 / 286 |
thymus | 100% | 2878.83 | 653 / 653 | 100% | 24.98 | 604 / 605 |
bladder | 100% | 2623.29 | 21 / 21 | 100% | 28.21 | 503 / 504 |
uterus | 100% | 2754.29 | 170 / 170 | 100% | 28.88 | 458 / 459 |
brain | 100% | 4528.97 | 2636 / 2642 | 100% | 32.78 | 705 / 705 |
breast | 100% | 2266.71 | 459 / 459 | 100% | 33.04 | 1115 / 1118 |
kidney | 100% | 2128.58 | 89 / 89 | 99% | 20.91 | 896 / 901 |
lung | 99% | 1932.82 | 574 / 578 | 100% | 31.06 | 1153 / 1155 |
pancreas | 94% | 978.26 | 309 / 328 | 99% | 20.81 | 176 / 178 |
liver | 87% | 884.05 | 196 / 226 | 91% | 10.05 | 369 / 406 |
adipose | 100% | 2131.09 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 19.96 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 14.19 | 29 / 29 |
spleen | 100% | 1295.00 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 26.10 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 21.22 | 1 / 1 |
blood vessel | 100% | 2590.11 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2768.62 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 95% | 1844.94 | 819 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 84% | 1624.34 | 777 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000086 | Biological process | G2/M transition of mitotic cell cycle |
GO_0006482 | Biological process | protein demethylation |
GO_0005654 | Cellular component | nucleoplasm |
GO_0004864 | Molecular function | protein phosphatase inhibitor activity |
GO_0051722 | Molecular function | protein C-terminal methylesterase activity |
GO_0045296 | Molecular function | cadherin binding |
GO_0051721 | Molecular function | protein phosphatase 2A binding |
GO_0019888 | Molecular function | protein phosphatase regulator activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0051723 | Molecular function | protein methylesterase activity |
GO_0106222 | Molecular function | lncRNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0019903 | Molecular function | protein phosphatase binding |
Gene name | PPME1 |
Protein name | Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89) |
Synonyms | PP2593 PRO0750 PME1 |
Description | FUNCTION: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. . |
Accessions | Q9Y570 ENST00000398427.6 [Q9Y570-4] ENST00000328257.13 [Q9Y570-1] |