Name | Number of supported studies | Average coverage | |
---|---|---|---|
transit amplifying cell | 3 studies | 26% ± 8% |
Insufficient scRNA-seq data for expression of CDC25C at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 91% | 216.89 | 1643 / 1809 | 85% | 5.12 | 403 / 472 |
intestine | 56% | 75.98 | 541 / 966 | 96% | 9.35 | 505 / 527 |
stomach | 53% | 51.91 | 191 / 359 | 97% | 8.59 | 277 / 286 |
lung | 58% | 31.65 | 338 / 578 | 84% | 5.61 | 966 / 1155 |
esophagus | 43% | 49.49 | 619 / 1445 | 96% | 7.39 | 176 / 183 |
bladder | 19% | 7.05 | 4 / 21 | 93% | 8.54 | 470 / 504 |
breast | 21% | 8.04 | 96 / 459 | 87% | 6.73 | 976 / 1118 |
ovary | 9% | 4.47 | 16 / 180 | 96% | 8.63 | 413 / 430 |
uterus | 8% | 3.19 | 13 / 170 | 97% | 12.81 | 446 / 459 |
lymph node | 0% | 0 | 0 / 0 | 100% | 7.58 | 29 / 29 |
tonsil | 0% | 0 | 0 / 0 | 100% | 14.57 | 45 / 45 |
spleen | 95% | 93.06 | 230 / 241 | 0% | 0 | 0 / 0 |
liver | 21% | 16.60 | 47 / 226 | 66% | 4.07 | 268 / 406 |
peripheral blood | 82% | 209.96 | 758 / 929 | 0% | 0 | 0 / 0 |
adrenal gland | 53% | 19.67 | 136 / 258 | 23% | 1.54 | 54 / 230 |
pancreas | 9% | 2.34 | 28 / 328 | 64% | 3.02 | 114 / 178 |
brain | 29% | 6.23 | 759 / 2642 | 39% | 2.71 | 278 / 705 |
prostate | 33% | 10.68 | 81 / 245 | 17% | 0.69 | 86 / 502 |
kidney | 21% | 10.29 | 19 / 89 | 12% | 0.52 | 108 / 901 |
thymus | 14% | 3.95 | 94 / 653 | 14% | 1.69 | 85 / 605 |
adipose | 24% | 8.82 | 285 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 11% | 3.03 | 152 / 1335 | 0% | 0 | 0 / 0 |
heart | 8% | 2.44 | 67 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 8% | 0.19 | 6 / 80 |
muscle | 2% | 0.48 | 14 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007283 | Biological process | spermatogenesis |
GO_0010971 | Biological process | positive regulation of G2/M transition of mitotic cell cycle |
GO_0008283 | Biological process | cell population proliferation |
GO_0000079 | Biological process | regulation of cyclin-dependent protein serine/threonine kinase activity |
GO_0051301 | Biological process | cell division |
GO_0000086 | Biological process | G2/M transition of mitotic cell cycle |
GO_0110032 | Biological process | positive regulation of G2/MI transition of meiotic cell cycle |
GO_0007088 | Biological process | regulation of mitotic nuclear division |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005758 | Cellular component | mitochondrial intermembrane space |
GO_0005634 | Cellular component | nucleus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0004721 | Molecular function | phosphoprotein phosphatase activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0050699 | Molecular function | WW domain binding |
GO_0005515 | Molecular function | protein binding |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | CDC25C |
Protein name | M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C) M-phase inducer phosphatase (EC 3.1.3.48) Cell division cycle 25C splice variant 3 Cell division cycle 25C |
Synonyms | |
Description | FUNCTION: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle . When phosphorylated, highly effective in activating G2 cells into prophase . Directly dephosphorylates CDK1 and activates its kinase activity . . FUNCTION: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. . |
Accessions | ENST00000513970.5 [P30307-1] A0A3B3IT42 ENST00000648466.1 ENST00000510119.1 H0Y999 ENST00000323760.11 [P30307-1] P30307 ENST00000415130.6 [P30307-4] D6RJC2 ENST00000503022.5 ENST00000514555.5 [P30307-2] ENST00000514017.1 D6RD20 Q9H2F0 |