CDC25C report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDC25C at tissue level.

III. Associated gene sets

GO_0007283Biological processspermatogenesis
GO_0010971Biological processpositive regulation of G2/M transition of mitotic cell cycle
GO_0008283Biological processcell population proliferation
GO_0000079Biological processregulation of cyclin-dependent protein serine/threonine kinase activity
GO_0051301Biological processcell division
GO_0000086Biological processG2/M transition of mitotic cell cycle
GO_0110032Biological processpositive regulation of G2/MI transition of meiotic cell cycle
GO_0007088Biological processregulation of mitotic nuclear division
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005758Cellular componentmitochondrial intermembrane space
GO_0005634Cellular componentnucleus
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0004721Molecular functionphosphoprotein phosphatase activity
GO_0019901Molecular functionprotein kinase binding
GO_0050699Molecular functionWW domain binding
GO_0005515Molecular functionprotein binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameCDC25C
Protein nameM-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C)
M-phase inducer phosphatase (EC 3.1.3.48)
Cell division cycle 25C splice variant 3
Cell division cycle 25C
Synonyms
DescriptionFUNCTION: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle . When phosphorylated, highly effective in activating G2 cells into prophase . Directly dephosphorylates CDK1 and activates its kinase activity . .

FUNCTION: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. .

AccessionsENST00000513970.5 [P30307-1]
A0A3B3IT42
ENST00000648466.1
ENST00000510119.1
H0Y999
ENST00000323760.11 [P30307-1]
P30307
ENST00000415130.6 [P30307-4]
D6RJC2
ENST00000503022.5
ENST00000514555.5 [P30307-2]
ENST00000514017.1
D6RD20
Q9H2F0